IntroductionAchieving appropriate anesthesia in mandibular molar teeth with irreversible pulpitis is one of the most challenging aspects of root canal treatment.1 It is more complicated in teeth with symptomatic irreversible pulpitis.2 Inferior alveolar nerve block is not profoundly successful in mandibular teeth with symptomatic irreversible pulpitis and sometimes supplemental techniques are necessary.
3Nowadays photobiomodulation (PBM) is considered as an adjunct in anesthesia, the addition of galliumaluminum-arsenide laser irradiation to intravenous regional anesthesia is safe, and reduces pain during and after the operation. The most local anesthetics in dentistry block sodium channels. Tetrodotoxin resistance sodium channels are resistant to local anesthetics and sensitized by prostaglandins.
5PBM has been used in dentistry for its anti-inflammatory, 6 regeneration 7 and analgesic 4 properties. It can prevent nerve impulse conduction. Studies have shown that laser irradiation prevents axonal transmission of signals in nerve fibers A-delta and C, since nociceptive signals are transmitted by the fibers of to the spinal cord, it is likely that laser radiation reduces the transmission and subsequently reduces the feeling of pain.8 PBM effectiveness was shown in reducing pain after root canal therapy, 9 but it hasn't been used as an adjunct in anesthesia in dentistry. Some PBM applications in dentistry include the following: To control pain, swelling and inflammation after surgery thus reducing the need for medication.
10To reduce pain after tooth fillings or dentin cutting with an inhibitory effect on the pulp nervous system.
11The anti-inflammatory mechanism of PBM and its Abstract Introduction: Achieving appropriate anesthesia in patients with symptomatic irreversible pulpitis in mandibular molars during endodontic treatment is always one of the most challenging aspects. Photobiomodulation (PBM) has been used in dentistry due to its anti-inflammatory properties and regenerative effects. This study evaluates the effects of PBM in the depth of anesthesia in inferior alveolar nerve block.
Methods:In this randomized clinical trial, 44 patients requiring endodontic treatment in lower molar, left or right were selected, half of them were randomly treated with PBM therapy. Laser irradiation by 980 nm diode laser with a single dose (15 J/cm 2 , for 20 seconds) before anesthesia was performed at the buccal aspect. Inferior alveolar nerve block was performed once. Success was defined as no or mild pain (no need for any supplemental injection), based on the visual analogue scale during access cavity preparation. Results were evaluated using SPSS software.
Results:The results of this study showed that the necessity for supplemental injection was lower in the group receiving laser than in the group without laser (P = 0.033). The mean pain intensity during dentin cutting was lower in the group receiving laser than in the group without laser (P = 0.031). Also, the mean pain intensity during pulp dropping was lower in the gr...