Fairy tales and storytelling: impromptu speaking with a twist

Which way up? Recognition of homologous DNA segments in parallel and antiparallel alignments

“…58 Global homology recognition through helix distortions may not be the complete search mechanism, even in the absence of strand breakage. 59 There is some evidence 46 to suggest the importance of an interaction that recognizes homology at the local level of individual base pairs, yet the nature of this interaction remains unclear. However, as homologous pairing was shown not to depend on the exact nature of the base pair text, 46 those results seem to rule out the stem loop kissing mechanism.…”

“…The theoretical implications of such a contribution to homology recognition have yet to be investigated, and may be the topic for further work. 59 However, the contribution of such an interaction alone would likely yield a very narrow recognition well, which would be determined by short range interactions. Hence, this mechanism alone would probably engender a long homology search.…”

“…Such specially designed experiments, in controlled conditions, may help to further elucidate the relative importance of various homology pairing mechanisms. 59 …”

“…Hence, this mechanism alone would probably engender a long homology search. 59 Thus, we think that the global recognition mechanism due to base-pair specific helix distortions is important in providing a fast initial recognition step.…”

The Impromptu Gauntlet

“…Most guidelines for evaluating presentations advocate the consideration of speech content and speech delivery separately (Locker & Kienzler, 2012;Pittenger, Miller, & Mott, 2004;Russell & Munter, 2013;Thill & Bovée, 2013), leading some instructors to develop assignments that focus exclusively on one element of the speaking process (e.g., see Hoger, 2012;Prentiss, 2004). Although the benefits of this approach are apparent, these activities still provide students with a limited amount of actual speaking experience with an audience.…”