Falldefinitionen für die Surveillance meldepflichtiger Infektionskrankheiten in Deutschland, Ausgabe 2015

Diercke, Michaela; Benzler, Justus; Schöneberg, Irene; Mücke, Inge; Altmann, Doris; Claus, H.; Gilsdorf, Andreas; Infektionsepidemiologie, Mitarbeiter der Abteilung für

doi:10.1007/s00103-014-2023-3

Cited by 9 publications

(3 citation statements)

References 4 publications

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“…The case definition was strict concerning time, place and person, which allowed us to rely on unspecific symptoms such as fever without laboratory confirmation. This approach is compatible with the surveillance case definition according to the German infectious disease law, in which leptospirosis cases are defined based on the occurrence of clinical symptoms in conjunction with contact to or joint exposure with laboratory-confirmed patients (Diercke et al, 2014;Höhl, 2020).…”

Section: Discussionmentioning

confidence: 90%

“…For systematic data analysis, we defined cases according to the German surveillance case definition (Diercke et al, 2014) which is almost identical to the European case definitions (The European Commission, 2018). They include laboratory-confirmed cases as confirmed cases and clinical cases with epidemiological link to laboratory-confirmed cases as probable cases.…”

Section: Case Definitionmentioning

confidence: 99%

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Investigation and response to a large outbreak of leptospirosis in field workers in Lower Saxony, Germany

Dreesman¹,

Toikkanen²,

Runge

et al. 2023

Zoonoses and Public Health

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Between June and August 2014, 45 cases of leptospirosis were notified among workers on two strawberry farms in North-West Germany. We describe the characteristics of the outbreak and the actions taken to prevent further cases. The activities of the local, federal and national public health and veterinary authorities included collection of case data, laboratory testing of human specimens and of small mammals trapped on the fields, investigation of weather data, as well as information provided to farmers, field workers, physicians and to the authorities in Poland and Romania. Of the 45 identified cases (median age 22, 60% male), 47% were hospitalized. Characteristic symptoms were fever ≥38.5°C, generalized muscle pain and an increase in renal or liver enzymes. Thirteen cases were laboratory confirmed by serological and/or molecular methods. ELISA tests for Leptospira IgG and IgM-antibodies were positive in those samples taken >5 days after hospitalization. The probable causative agent was identified as Leptospira kirschneri serovar Grippotyphosa. Leptospira-specific DNA was found in kidneys of 67% of 64 trapped small mammals and was further identified as Leptospira kirschneri multi locus sequence type 110. During the estimated time period of human infections, the affected region faced warm weather with heavy rainfalls.The results of this investigation are in accordance with the theory of a chain of infection from mice to field workers during warm and humid weather. In 2015, a campaign was initiated to inform physicians, farmers and workers to enhance prevention measures, such as the use of personal protective equipment and early consultation of physicians in case of illness. Since then, no further outbreak occurred.

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Section: Discussionmentioning

confidence: 90%

Section: Case Definitionmentioning

confidence: 99%

Investigation and response to a large outbreak of leptospirosis in field workers in Lower Saxony, Germany

Dreesman¹,

Toikkanen²,

Runge

et al. 2023

Zoonoses and Public Health

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show abstract

“…On the other hand, our results also suggest that many hepatitis B cases considered relevant for disease burden may have already been notified to LHDs, although not required by the notification law, and thus can be used for estimation of disease incidence and epidemiological analyses. In 2015 an update of the German case and reference definitions has been published that requires that hepatitis B cases without symptoms of acute hepatitis are included in the calculation of diseases incidences (they meet the reference definition) [20]. Additionally, in 2017 the notification requirements were changed so that laboratories have to notify every case of hepatitis B or C they detect regardless of clinical symptoms and course of disease (acute or chronic).…”

Section: Discussionmentioning

confidence: 99%

Positive predictive value of the German notification system for infectious diseases: Surveillance data from eight local health departments, Berlin, 2012

Blümel

Diercke

Sagebiel³

et al. 2019

PLoS ONE

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The German Infection Protection Act requires notifying certain cases of infectious diseases to local health departments (LHD) in Germany. LHDs transmit notifications meeting case definitions to the national health authority, where the proportion of discarded notifications is not known. The proportion of discarded cases at the level of LHDs can be expressed as the positive predictive value (PPV) of the notification system. The PPV can be used to assess the efficiency of the system. We quantified the proportion of discarded notifications to calculate the PPV of the German notification system at the level of LHDs using electronic notification data from Berlin LHDs from 2012. We also analysed reasons for discarding notifications by reviewing notification forms. Data was available from eight LHDs (67%) receiving 10,113 notifications in 2012. Overall PPV was 89% (minimum-maximum = 77–97% across LHDs) and ranging from 30% (Hepatitis B) to 99% (Rotavirus). Of 166 individual investigation forms 84% were on hepatitis B or C cases, most of them discarded because of previously diagnosed chronic disease. LHDs investigate many notifications that do not lead to public health action and useful surveillance data leading to inefficient use of resources. Adaptation of case definitions or the legal framework concerning notifications may increase the efficiency of the notification system and lead to better use of data from notified cases.

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Diagnosis and Treatment of Neglected Tropical Diseases in Europe: Laboratory Infrastructure, Diagnostic Techniques, Disease Notification, and Surveillance Systems

Becker

2021

Neglected Tropical Diseases

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Falldefinitionen für die Surveillance meldepflichtiger Infektionskrankheiten in Deutschland, Ausgabe 2015

Cited by 9 publications

References 4 publications

Investigation and response to a large outbreak of leptospirosis in field workers in Lower Saxony, Germany

Investigation and response to a large outbreak of leptospirosis in field workers in Lower Saxony, Germany

Positive predictive value of the German notification system for infectious diseases: Surveillance data from eight local health departments, Berlin, 2012

Diagnosis and Treatment of Neglected Tropical Diseases in Europe: Laboratory Infrastructure, Diagnostic Techniques, Disease Notification, and Surveillance Systems

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