Falling through the cracks of vasculitis classification--a report of three patients

Persistent or New Onset Microscopic Hematuria in Patients with Small Vessel Vasculitis in Remission: Findings on Renal Biopsy

“…Among the 3 patients that underwent renal biopsy for evaluation of new-onset hematuria, 2 had crescentic IgA nephropathy. It is important to recognize that AAV can overlap with other types of vasculitis 9 . In addition, ANCA-associated necrotizing GN has been frequently reported to occur superimposed upon other glomerular disease processes, including IgA nephropathy 10 , membranous nephropathy 11 , acute postinfectious GN 12 , lupus nephritis 13 , and even diabetic glomerulosclerosis 14 .…”

A case of IgA vasculitis with necrotizing arteritis in a 13-year-old girl

“…Whether the patients had pre-existing vasculitis superimposed on or overlapped by another vasculitis remains unclear. Havill et al [10] pointed out three possibilities: (1) truly coincidental; (2) the two different vasculitides represented another disease that cannot be classified by the current classification; and (3) as one autoimmune disease more likely to develop another autoimmune disease, the two different diseases could be related at a molecular and genetic level. In either case, it is important to make a prompt diagnosis and consider aggressive therapy given the rapid exacerbations in recent reports.…”