Fallo hepático fulminante secundario a infiltración maligna hepática

Barreales, M.; Casís, Begoña; López, Sabrina; Herruzo, J. A. Solís

doi:10.4321/s1130-01082007000400016

Cited by 2 publications

(4 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Hematological malignancies are recognized to be the most common cause of diffuse parenchymal metastasis (1,3,4). This metastatic pattern has also been identified in many primary neoplasms, including breast, lung, stomach, colon, pancreatic, nasopharynx, urothelial, uterine and malignant melanoma (3,4,7,8). …”

Section: Discussionmentioning

confidence: 76%

“…This complication is speculated to be caused by extensive hepatocellular necrosis resulting from pressure atrophy and interference of the vascular supply (4,6–8,13). Radiological studies including ultrasonography, CT and MRI scans are usually not able to identify diffuse parenchymal metastasis (1,3–5,7), thus increasing the difficulty in the diagnosis.…”

Section: Discussionmentioning

confidence: 99%

“…The prognosis of acute liver failure secondary to malignant infiltration is extremely poor; the majority of patients do not survive shortly after the onset of liver failure (1–4,7,8). According to a review by Allison et al , concerning 21 reported cases of acute liver failure due to metastatic breast carcinoma, 18 cases died within three days to two months (7).…”

Section: Discussionmentioning

confidence: 99%

“…Diffuse parenchymal metastasis is a rare pattern of liver metastasis that is correlated with hepatic failure and an extremely poor prognosis (1–8). Unlike the usual patterns of liver metastasis, radiological studies are typically not able to detect this type of pattern (1,3–5,7).…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Acute liver failure associated with diffuse liver infiltration by metastatic breast carcinoma: A case report

Hanamornroongruang

Sangchay

2013

Oncology Letters

View full text Add to dashboard Cite

Diffuse parenchymal metastasis is an unusual pattern of liver metastasis that is capable of causing liver failure. In the present study, the authors describe malignant infiltration of the liver by primary breast carcinoma in an autopsy of a 49-year-old female who had a rapid onset of liver failure and died after three weeks. Ultrasonography and computed tomography (CT) scans of the abdomen, as well as macroscopic examination, failed to detect liver metastasis; while microscopic examination revealed diffuse tumor cells with a loss of E-cadherin expression infiltrating into the liver parenchyma. The prognosis of liver failure associated with malignant infiltration is extremely poor; the survival time of patients is extremely low. Liver biopsy may be the most efficient technique for confirming the diagnosis during the patient’s life.

show abstract