Fallopian tube adenocarcinoma in situ assosiated with adjuvant Tamoxifen therapy-A case report-

Early detection of ovarian and fallopian tube cancer by examination of cytological samples from the endometrial cavity

“…Little information regarding long-term outcomes is available for most reported cases of cytology-detected fallopian tube cancer. However, a patient with serous TIC with positive findings on peritoneal cytology, who also had a personal history of breast cancer, survived for >7 years despite two recurrences (Gocho et al , 2009). In our study, two of the four asymptomatic cytology-detected patients survived for ⩾5 years without a recurrence, even with delayed treatment.…”

“…Several case reports have shown that endometrial cytological tests developed to screen endometrial cancer (Ferenczy and Gelfand, 1984; Byrne, 1990) can detect intraepithelial and microinvasive fallopian tube carcinomas (Ikarashi et al , 1995; Luzzatto et al , 1996; Minato et al , 1998; Gocho et al , 2009, Maeda et al , 2010). In Japan, endometrial cancer screening using such cytological tests is widely performed for women at risk of the disease (Tsuda et al , 1997), including breast cancer patients treated with tamoxifen (Gocho et al , 2009; Otsuka et al , 2010), and women who request the screening. In the present study, we examined the data of patients with epithelial ovarian, fallopian tube, and primary peritoneal cancer to evaluate the role of endometrial cytological testing in detecting HGSC, particularly for screening setting.…”