Falls-Related Drug Use and Risk of Falls Among Older Adults: A Study in a US Medicare Population

Wang, Shaohung S.; Ruiz, Joann; Hawkins, Kevin; Wicker, Ellen

doi:10.1007/s40266-017-0470-x

Cited by 34 publications

(30 citation statements)

References 32 publications

(76 reference statements)

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“…In this group there was not much difference between the number of comorbidities in the two groups and polypharmacy was also widely prevalent. A study by Musich et al, found that in new and continuing fall‐related drug (FRD) users the fall rates were 7% and 8%, respectively, which also provides a platform for the polygenetic etiology of falls. In a study by Early et al, it was noted that fall rates increased with >6 FRDs in the 65‐74 age group and >5 FRDs in the 75‐84 age group.…”

Section: Discussionmentioning

confidence: 99%

Prevalence and predictors of falls in a health‐seeking older population: An outpatient‐based study

et al. 2020

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Background Falls are one of the major causes of disability in older people. A wide range of risk factors for falls are described according to setting – inpatient, nursing homes and community. The aim of this study was to identify the risk factors for falls in an outpatient setting. Methods In this cross‐sectional observational study, 160 consenting subjects were enrolled randomly, from the Geriatric Medicine outpatient department, All India Institute of Medical Sciences, New Delhi, India. Non‐ambulatory, seriously ill subjects were excluded. The subjects underwent brief evaluation including falls and geriatric assessment. They were grouped into fallers and non‐fallers. A multivariable logistic regression analysis was used to identify the factors associated with falls. Results The prevalence of falls was 23.75% (38/160). Women were proportionately higher (26.31%) in the fallers group vis‐à‐vis 19.67% in the non‐fallers group. After multivariate analysis, opioids (odds ratio [OR] 5.24 [95% CI, 2.0 18‐13.611]), vision impairment (OR 2.71 [95% CI, 1.050‐07.011]), fear of falling (OR 3.17 [95% CI, 1.167‐08.629]), instrumental activity of daily living (IADL) impairment (OR 3.41 [95% CI, 1.251‐09.301]), anti‐anginal medications (OR 8.90 [95% CI, 0.997‐79.564]) and self‐employment (OR 5.37 [95% CI, 1.058‐27.329]) were associated with falls. Adequate nutrition (OR 0.82 [95% CI, 0.688‐00.976]) and caregiver support (OR 0.46 [95% CI, 0.275‐00.801]) were protective of falls. Conclusion We identified the multi‐factorial etiology of falls. Patients having any of the above risk factors should undergo detailed fall risk assessment and preventive measures afterwards.

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Section: Discussionmentioning

confidence: 99%

Prevalence and predictors of falls in a health‐seeking older population: An outpatient‐based study

et al. 2020

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“…Sedation and postural hypotension by antidepressants and beta-blockers and the hypoglycemic effect of insulin also significantly contribute to the incidence of falls in the elderly. 5 , 18 , 37 , 38 In addition, the use of diuretics and laxatives cause the elderly to get up frequently and rush at a fast pace to use the toilet, usually without assistance thus increasing the risk of falls.…”

Section: Discussionmentioning

confidence: 99%

“… 5 , 14 , 15 , 16 Furthermore, cardiovascular drugs such as diuretics and beta-blockers may cause or worsen orthostatic hypotension and falls. 17 , 18 Antihistamines and anticholinergic drugs may affect the cognitive skills of elderly patients and cause blurred vision, thereby increasing the risk of falls. 19 It has also been stressed by the same authors that polypharmacy and the use of psychotropic drugs, especially when combined with cardiovascular medications increase the risk of falls in the elderly.…”

Section: Introductionmentioning

confidence: 99%

Falls in the elderly: assessment of prevalence and risk factors

Sharif¹,

Al-Harbi²,

Al-Shihabi³

et al. 2018

Pharm Pract (Granada)

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Background:Falls in elderly people can lead to serious health problems. There is limited knowledge about the prevalence of falls, risk factors and causes of falls in the United Arab Emirates.Objective:To assess the prevalence of falls among older adults aged 60 years and above and to determine the risk factors associated with falls.Methods:This cross-sectional study was conducted using an anonymous, 20-item questionnaire which was developed in English and Arabic to be delivered as a semi-structured interview. The pre-piloted questionnaire was distributed to 510 families with at least one elderly person. The study was conducted in Sharjah and Dubai, United Arab Emirates, from September to November 2017.Results:Participants were Arabs (368; 99.5%), living with family (339; 91.6%), females (256; 69.2%), married (240; 64.9%), holders of a university Bachelor’s degree (110; 29.7%), and unemployed (154; 41.6%). Almost half of the participants (188; 50.8%) had a fall in the past two years, and three quarters (141; 75%) of those claimed that their illness was the reason for their fall. The results indicate that female and 70 years and above old participants are more likely to experience falls than males and younger counterparts respectively. A larger proportion of elderly participants not taking medications did not experience falls, while those on 1-4 medications fallers were less than non-fallers. However as the number of medications increased to 5-8 and more than 8 the number of those experiencing falls was significantly higher than non-fallers.Conclusions:Falls are prevalent among the elderly population studied and efforts should be made to decrease the incidence of falls, identify those at risk and increase awareness about falls and their health consequences among the elderly and the general public.

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“…Furthermore, those in the older adult population are at risk of falls, and the use of drugs may increase the risk of falls. Most research regarding drug use and falls have focused on prescription drugs, not marijuana use ( Musich, Wang, Ruiz, Hawkins, & Wicker, 2017 ).…”

Section: Discussionmentioning

confidence: 99%

Marijuana Use Among Adults 50 Years or Older in the 21st Century

Lloyd

Striley

2018

Gerontology and Geriatric Medicine

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Background: Marijuana is the most commonly used illicit drug among older adults. As an older population grows in the United States that has a tolerant attitude toward marijuana use, the dynamics of marijuana use and the effects of marijuana on personal, social, and health outcomes among older adults require attention. Objectives: This review summarizes epidemiological literature on marijuana use among older adults. Method: A literature search was conducted using PubMed, AgeLine, and an online search engine from January 2000 to December 2017, resulting in 18 articles. Results: The greatest increase in marijuana use was observed among those in the older adult population 50 years or older, and those 65 years or older had the greatest increase in marijuana use in the older adult population. Common correlates of marijuana use among those in the older population included being male, being unmarried, having multiple chronic diseases, having psychological stress, and using other substances such as alcohol, tobacco, other illicit drugs, and prescription drugs. Conclusion: The increased use of marijuana in older populations requires surveillance and additional research to understand the use and effects of marijuana in older populations to avoid negative health outcomes.

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Falls-Related Drug Use and Risk of Falls Among Older Adults: A Study in a US Medicare Population

Cited by 34 publications

References 32 publications

Prevalence and predictors of falls in a health‐seeking older population: An outpatient‐based study

Prevalence and predictors of falls in a health‐seeking older population: An outpatient‐based study

Falls in the elderly: assessment of prevalence and risk factors

Marijuana Use Among Adults 50 Years or Older in the 21st Century

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