False amblyopia prediction in strabismic patients by fixation preference testing correlates with contralateral ocular dominance

AlHarkan, Dora H.; Khan, Arif O.

doi:10.1016/j.jaapos.2014.06.010

Cited by 6 publications

(5 citation statements)

References 11 publications

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“…2 Treatments include laser in situ keratomileusis (LASIK), multifocal intraocular lens implantation, and other refractive surgeries that use monocular vision correction for the treatment of presbyopia, strabismus, amblyopia, and nystagmus. 3,4 Previous controversy remains regarding where to center corneal refractive procedures to maximize visual outcomes. 5 The angle kappa is defined as the angle between the visual axis and the pupillary axis.…”

Section: Resultsmentioning

confidence: 99%

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Comparative study of refractive and visual quality after wavefront-optimized FS-LASIK for angle kappa adjustment in dominant and nondominant eyes

Lin

Liu

Zhao

et al. 2023

J Cataract Refract Surg

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Section: Resultsmentioning

confidence: 99%

mentioning

confidence: 99%

Comparative study of refractive and visual quality after wavefront-optimized FS-LASIK for angle kappa adjustment in dominant and nondominant eyes

Lin

Liu

Zhao

et al. 2023

J Cataract Refract Surg

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“…Alharkan and Khan 16 investigated the reasons for misinterpretation of binocular fixation pattern testing and found that contralateral ocular dominance may interfere with the test results and cause a false prediction of amblyopia.Ocular dominance was not identified in the present study.…”

Section: Discussionmentioning

confidence: 99%

Is Fixation Preference a Potential Indicator of Macular Function in Children?

Şekeroğlu¹,

Bilgiç²,

Karakaya³

2021

tjo

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Objectives: Fixation preference testing is widely used to detect amblyopia, particularly in preverbal children. Pattern electroretinogram (pERG) is an electrophysiological test which is a sensitive indicator of macular function. The aim of this study was to investigate the relationship between fixation preference and macular function on pERG in children with strabismus. Materials and Methods: The study included 11 children with strabismus. All underwent ophthalmological examination including fixation preference by binocular fixation pattern test, best corrected visual acuity (BCVA) assessment, and pERG. Results: The mean age of the patients was 10.09±1.18 years. All patients had unilateral fixation. The mean BCVA was 0.85±0.17 in preferred and 0.48±0.19 in non-preferred eyes (p=0.003). The mean p50 amplitude was 6.07±2.06 μV in preferred and 5.29±2.20 μV in non-preferred eyes (p=0.203), and the mean N95 amplitude was 8.27±2.86 μV and 8.03±3.24 μV respectively (p=0.594). BCVA was correlated with p50 and N95 amplitudes in the non-preferred eyes (p=0.023 and p=0.014). Interocular BCVA difference was correlated with interocular P50 amplitude difference (r=0.688, p=0.019). Conclusion: Although amblyopia is typically considered a cortical phenomenon, future larger studies are needed to investigate the relationship between fixation preference and macular electrophysiological function.

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“…The non‐fixing, habitually deviating eye is presumed to be amblyopic. However, this test has a high false positive rate, such that the test appears to be more useful for predicting the absence rather than the presence of amblyopia in strabismic children …”

Section: Part B: Diagnosis Of Amblyopiamentioning

confidence: 99%

A pragmatic approach to amblyopia diagnosis: evidence into practice

Webber

Camuglia

2018

Clinical and Experimental Optometry

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Amblyopia is a common cause of reduced vision in children. The clinical diagnosis is complicated and requires consideration of the severity of vision loss relative to the characteristics of the disrupting amblyogenic factor. Added to the challenge of a thorough examination of very young children, is the weight of consequence if the amblyogenic factor is not identified and treated appropriately within clinically recommended time frames. Further, the poor visual function may be a symptom of more sinister underlying pathology impacting the visual pathway. This review presents an evidence-based, pragmatic approach to the diagnosis of amblyopia, as a means for guiding best practice for the care of children who present with reduced vision.

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False amblyopia prediction in strabismic patients by fixation preference testing correlates with contralateral ocular dominance

Cited by 6 publications

References 11 publications

Comparative study of refractive and visual quality after wavefront-optimized FS-LASIK for angle kappa adjustment in dominant and nondominant eyes

Comparative study of refractive and visual quality after wavefront-optimized FS-LASIK for angle kappa adjustment in dominant and nondominant eyes

Is Fixation Preference a Potential Indicator of Macular Function in Children?

A pragmatic approach to amblyopia diagnosis: evidence into practice

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