False-positive serum human chorionic gonadotropin results: Causes, characteristics, and recognition

Braunstein, Glenn D.

doi:10.1067/mob.2002.124284

Cited by 68 publications

(44 citation statements)

References 52 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Normally produced by the syncytiotrophoblastic cells of the placenta, hCG is commonly used as a marker for pregnancy detection and monitoring. Serum concentrations of hCG also have clinical use as tumor markers for trophoblastic diseases, germ cell tumors, and other malignancies (7,8 ). Because hCG measurements have two clinical applications, false-positive hCG results not only cause clinical confusion, but in several instances have led to harmful therapeutic interventions (6 ).…”

mentioning

confidence: 99%

Diagnostic Considerations in the Measurement of Human Chorionic Gonadotropin in Aging Women

et al. 2005

View full text Add to dashboard Cite

mentioning

confidence: 99%

Diagnostic Considerations in the Measurement of Human Chorionic Gonadotropin in Aging Women

et al. 2005

View full text Add to dashboard Cite

“…4 Several reports in the literature document the production of hCG b-core fragment by common epithelial tumours, including colon and bladder. In addition false-positive urine hCG results have been reported in people with nephritic range proteinuria, systemic lupus erythematosus, ovarian failure and elevated gonadotrophins and tubo-ovarian abscess.…”

Section: Discussionmentioning

confidence: 99%

“…4 The current use of modern immunometric assays (antibody-dye/hCG/immobilised antibody) in urinary pregnancy tests has decreased the risk of falsepositive results significantly. 5 In the circulation, the bulk of the hCG exists as intact hormone whereas in urine a large fraction of the immunoreactivity of hCG is the result of a metabolic breakdown product known as b-core fragment.…”

Section: Discussionmentioning

confidence: 99%

False‐positive pregnancy tests following enterocystoplasty

Nakhal¹,

Wood

Woodhouse

et al. 2011

BJOG

View full text Add to dashboard Cite

People with major congenital urological or neurological malformations invariably require bladder reconstruction with enterocystoplasty in early childhood. The improvement of the surgical management of these children has reflected significantly on their life expectancy. As a result, more young people with enterocystoplasty are being transitioned to adolescent clinics where they receive the usual counselling about sexual health and pregnancy risks. However, the possibility of false-positive urinary pregnancy tests in these young women remains an overlooked but essential message. The lack of awareness about this fact can result in significant patient anxiety and the potential for unnecessary interventions as exemplified by the three cases we have encountered.

show abstract

“…İn-sidansı 1/1000 ila 1/10000 arasındadır. 3 Bu yanlış pozitif sonuçların yönetimde karışıklığa, kemoterapi, histerektomi ve cerrahi prosedürler gibi gereksiz tedavilere neden olabileceği unutulmamalıdır.…”

Section: A Ab Bs S T Tr Ra Ac Ct Tunclassified