1998
DOI: 10.1136/hrt.79.2.195
|View full text |Cite
|
Sign up to set email alerts
|

Familial atrial fibrillation with fetal onset

Abstract: A woman presented during two pregnancies (at 25 and 23 weeks' gestation, respectively) because the fetuses had rapid, irregular tachycardia and hydrops. After maternal drug treatment and achievement of slower fetal heart rates, the hydrops gradually resolved. Both babies were born full term with continuing atrial fibrillation. In the first, an ectopic atrial rhythm was temporarily achieved during high dose flecainide treatment but, in the younger sibling, all medications and repeated cardioversions failed even… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

0
9
0
3

Year Published

2000
2000
2013
2013

Publication Types

Select...
6
2
2

Relationship

0
10

Authors

Journals

citations
Cited by 24 publications
(12 citation statements)
references
References 11 publications
0
9
0
3
Order By: Relevance
“…Familial atrial fibrillation is very rare in the paediatric age group. It has been described in fetuses and in neonates with tachycardia but not with bradycardia [5–7]. Most patients had either structurally abnormal hearts or severe rheumatic heart disease [8,9], but our patient has a normal heart.…”
Section: Discussionmentioning
confidence: 73%
“…Familial atrial fibrillation is very rare in the paediatric age group. It has been described in fetuses and in neonates with tachycardia but not with bradycardia [5–7]. Most patients had either structurally abnormal hearts or severe rheumatic heart disease [8,9], but our patient has a normal heart.…”
Section: Discussionmentioning
confidence: 73%
“…It is frequently observed as a complication of a variety of cardiovascular and systemic disorders, such as hypertension, coronary artery disease, valvular heart disease, various forms of congenital heart disease, as well as cardiomyopathies. In rare occasion, fetal onset has been identifi ed (Tikanoja et al, 1998). In approximately 10-20% of cases, however, no underlying associated defect is identifi ed and, therefore, it is termed " idiopathic " or " lone " AF ( Brand et al, 1985 ).…”
Section: Atrial Fibrillation Clinical Aspectsmentioning
confidence: 99%
“…[17,18] In the past years, numerous case reports have been published in which flecainide proved to be successful as a single therapy or in combination with digoxin. [37,38,69,[78][79][80][81] In conclusion, flecainide is a successful drug in the treatment of fetal SVT. Of concern are the possible adverse effects experienced in the CAST study, [74] which could affect both mother and fetus; however, most studies on flecainide in the treatment of fetal tachycardias did not show any adverse effects.…”
Section: Clinical Experiencementioning
confidence: 99%