Familial benign chronic pemphigus. A papular variant

Witkowski, J. A.

doi:10.1001/archderm.108.6.842

Cited by 4 publications

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“…Mucosae are generally spared, although involvement of the esophagus (70,71), oral mucosa (72), ocular conjunctiva (24) and vulva Besides the classical description, morphological variations may also be seen. They may either be hyperkeratotic, papulovesicular, neurodermatitic, vesiculopustular (22), papular (74), or erythrodermic (56).…”

Section: Clinical Featuresmentioning

confidence: 99%

Chronic Familial Benign Pemphigus

Sehgal

Jain

1994

The Journal of Dermatology

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Section: Clinical Featuresmentioning

confidence: 99%

Chronic Familial Benign Pemphigus

Sehgal

Jain

1994

The Journal of Dermatology

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“…Hailey-Hailey disease is charaeterized by a recurrent vesiculobullous dermatitis that is sometimes widespread but more often confined to the axillae, groin, and neek and is complicated by erosion but not by scarring (1)(2)(3). Atypical cases have been reported with a hyperkeratotie verruccjus lesion, a papulovesicular lesion, a neurodermatitic lesion, a vesiculopustular lesion, or a papular lesion (3,4). It has been known to occur simultaneously with Da-rier's disease in some patients, leading to its classification by at least one investigator as a variant of Darier's disease (5,6).…”

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confidence: 99%

Squamous cell carcinoma arising in Hailey‐Hailey disease

Chun

Whang

1988

J Cutan Pathol

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A case of squamous cell carcinoma (SCC) arising in a lesion of Hailey-Hailey disease at the penoscrotal junction is reported. The patient was treated with arsphenamine (Salvarsan 606) early in the disease. It is possible that this carcinogen, as well as friction and the local irritation of long-standing Hailey-Hailey skin lesions, may be the predisposing factors for the development of SCC in this case.

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Hailey–Hailey disease: the clinical features, response to treatment and prognosis

Burge¹

1992

Br J Dermatol

273

270

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Fifty-eight individuals with Hailey-Hailey disease were studied to delineate the clinical features, response to treatment and prognosis. The disease generally presented between the second and fourth decades, but the morphology of lesions was varied and a delay in diagnosis was common. Nail changes have not been documented in previous studies of Hailey-Hailey disease, but asymptomatic longitudinal white bands were present in the fingernails in 71% of 38 patients examined and are a helpful physical sign. The disease is predominantly flexural. Friction and heat or sweating exacerbate the lesions and pain may limit physical activities. The prognosis was assessed in 27 patients with longstanding disease and the long-term outlook is generally good. Seventeen patients had improved and the disease was static in seven patients. Three patients deteriorated with age. Topical corticosteroids with or without added antibiotics were an effective treatment.

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Familial benign chronic pemphigus. A papular variant

Cited by 4 publications

References 0 publications

Chronic Familial Benign Pemphigus

Chronic Familial Benign Pemphigus

Squamous cell carcinoma arising in Hailey‐Hailey disease

Hailey–Hailey disease: the clinical features, response to treatment and prognosis

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