Familial cutaneous melanoma and two-mutational-event modeling

The association of host and genetic melanoma risk factors with Breslow thickness in the Western Australian Melanoma Health Study

“…Breslow thickness has been shown to be associated with host factors that are also associated with melanoma risk. Breslow thickness has been associated with increasing age at diagnosis, male sex and family history, with thinner melanomas diagnosed in individuals with a family history of melanoma . However, other studies have not found any evidence of the association between family history and Breslow thickness .…”