1991
DOI: 10.1002/art.1780340915
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Familial Erythema Nodosum

Abstract: Erythema nodosum (EN) is a hypersensitivity reaction associated with many diseases. We describe a family in which 4 sisters had acute or recurrent EN. HLA typing showed a common haplotype in the affected members of the family. A review of familial EN and HLA distribution in EN is presented.Erythema nodosum (EN) is considered to be an acute hypersensitivity reaction. It may occur alone or in association with various other diseases or certain medications (1,2). There have been a few reports of familial EN, mostl… Show more

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Cited by 4 publications
(2 citation statements)
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“…EN is seen more frequently in females (ratio 5:1) [1,3] and has a peak incidence between the ages of 18 and 34 years [1,3,5,6]. Familial EN has been reported [7], with affected family members showing a common HLA haplotype. The incidence of EN has decreased in the antibiotic era, with a current annual incidence of 1 to 5 per 100,000 persons [1,5,6].…”
Section: Epidemiologymentioning
confidence: 99%
“…EN is seen more frequently in females (ratio 5:1) [1,3] and has a peak incidence between the ages of 18 and 34 years [1,3,5,6]. Familial EN has been reported [7], with affected family members showing a common HLA haplotype. The incidence of EN has decreased in the antibiotic era, with a current annual incidence of 1 to 5 per 100,000 persons [1,5,6].…”
Section: Epidemiologymentioning
confidence: 99%
“…Так, O. Elkayam и соавт. [4] сообщили о развитии семейной УЭ, так как у всех членов семьи был установлен общий HLA-гаплотип. S. Labunski и соавт.…”
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