Familial hypophosphatemic vitamin D-resistant rickets: Dental findings and histologic study of teeth

Murayama, Takafumi; Iwatsubo, Reiko; Akiyama, Shuzo; Amano, Atsuo; Morisaki, Ichijiro

doi:10.1067/moe.2000.107522

Cited by 73 publications

(98 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…On the basis of clinical appearance, the differential diagnosis includes pustules, actinomycosis, osteomyelitis, hypophosphatemic Vitamin D resistant rickets, pyogenic granulomas, furuncles, neoplasms; squamous cell carcinomas, epidermal cysts, chronic tuberculosis and gumma of tertiary syphilis [4,5]. If a sinus tract does not close after an appropriate removal of the primary cause, the most common alternative cause is actinomycosis.…”

Section: Discussionmentioning

confidence: 99%

Non-Surgical Management of Mandibular Molar with Multiple Intra–oral Sinus Tracts: A Case Report

Gupta¹

2013

JCDR

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Non-Surgical Management of Mandibular Molar with Multiple Intra–oral Sinus Tracts: A Case Report

Gupta¹

2013

JCDR

View full text Add to dashboard Cite

“…The sequence of formati on of abscesses usually appears to follow the sequence of erupti on 35,39 . Hypophosphataemic pati ents have also been reported to display large interglobular spaces in the circumpulpal denti n 33,40 , whereas the mantle denti n is unaff ected 41 .…”

Section: Dental and Histologic Findingsmentioning

confidence: 99%

“…This phenomenon is associated with well documented oral and dental fi ndings 27,[30][31][32][33][34] . Hypophosphataemic vitamin D-resistant rickets have been atti ributed to the enlarged coronal pulp spaces and to the grossly defecti ve denti ne allowing ingress of micro-organism to the dental pulp once att riti on has removed the overlying protecti ve enamel 35,36 .…”

Section: Dental and Histologic Findingsmentioning

confidence: 99%

“…The enamel in some aff ected individuals has been described variously as relati vely thin, hypocalsifi ed or hypoplasti c, although it is not always obvious from the text which denti ti on is aff ected by these changes 36 . In general, both primary and permanent teeth have denti nal dysplasia 33 . The teeth usually show taurodonti sm, poorly defi ned lamina dura and a hypoplasti c alveolar ridge 36,37 .…”

Section: Dental and Histologic Findingsmentioning

confidence: 99%

“…Spontaneous periapical abscess formati on is also oft en observed in pati ents with XLH without dental caries or traumati c injury 30,38 . Because the teeth of pati ents with XLH are oft en associated with high pulp horns, large pulp chambers, and denti nal cleft s, it is believed that the abscesses are caused by pulpal infecti on that was caused by bacterial invasion through enamel cracks and denti nal microcleavage of the teeth 33 . Denti sts have diagnosed a few cases in which the systemic features were mild and dental abscesses were the fi rst presenti ng sign 31 .…”

Section: Dental and Histologic Findingsmentioning

confidence: 99%

See 2 more Smart Citations

Types of Rickets, Dental and Histologic Findings: Review of the Literature

Tümen¹

2009

Pesq Bras Odontoped Clin Integr

View full text Add to dashboard Cite

Introducti on: A disease that occurs during childhood, rickets is the failure of growing bone to mineralize. Many skeletal and radiographic changes can ocur because of the lack of calcifi ed osteoid and the buildup of unossifi ed carti lage. Proper bone formati on requires a complex interplay of several organs and chemicals, and vitamin D deserves special menti on because any disturbance in its producti on, absorpti on, or metabolism is paramount in the development of rickets. The pathophysiology of the disease is thought to be impaired phosphate transport, especially decreased phosphate resorpti on in the renal proximal tubule, as well as in the intesti ne. In most cases, the diagnosis is established with a thorough history and physical examinati on and confi rmed by laboratory evaluati on. Early diagnosis is essenti al because morbidity can be minimized if children are treated before eight months of age. Objecti ve: The aim of this literature review is to present various types of rickets with clinical features and the dental fi ndings, preventi ve measurements and treatments. Conclusion: The denti st as well as the pediatrician should be made aware of the features of this disorder so that early interventi on can prevent subsequent serious and more invasive dental procedures. KEYWORDS DESCRITORES Rickets;Hypophosphataemia; Oral manifestati ons; Therapeuti cs. RESUMO ABSTRACTIntrodução: O raquiti smo, uma doença que ocorre durante a infância, é a falta de crescimento ósseo necessário para a mineralização. Diversas alterações radiográfi cas esqueléti cas podem ocorrer devido a ausência de osteóide calcifi cado e a formação de carti lagem. A formação óssea adequada requer uma complexa interação de vários órgãos e produtos químicos, e a vitamina D merece uma menção especial, pois qualquer alteração na sua produção, absorção ou no seu metabolismo é fundamental para o desenvolvimento do raquiti smo. Acredita-se que a fi siopatologia da doença está no transporte inadequado do fosfato, especialmente na diminuição da reabsorção de fosfato no túbulo renal proximal bem como no intesti no. Na maioria dos casos, o diagnósti co é estabelecido com uma história completa e exame fí sico, e confi rmado por exames laboratoriais. O diagnósti co precoce é essencial, pois a morbidade pode ser minimizada se as crianças forem tratadas antes dos oito meses de idade. Objeti vo: Apresentar os vários ti pos de raquiti smo com suas característi cas clínicas, aspectos dentários, medidas preventi vas e tratamento. Conclusão: O cirurgião-denti sta, bem como o pediatra, devem ser informados das característi cas desta desordem para que a intervenção precoce possa evitar seqüelas subsequentes e procedimentos odontológicos mais invasivos.

show abstract

Oral Pathology and Oral Medicine

Chaar¹,

Kumar²

2022

Practical Techniques in Periodontics and Implant Dentistry

View full text Add to dashboard Cite

Familial hypophosphatemic vitamin D-resistant rickets: Dental findings and histologic study of teeth

Cited by 73 publications

References 16 publications

Non-Surgical Management of Mandibular Molar with Multiple Intra–oral Sinus Tracts: A Case Report

Non-Surgical Management of Mandibular Molar with Multiple Intra–oral Sinus Tracts: A Case Report

Types of Rickets, Dental and Histologic Findings: Review of the Literature

Oral Pathology and Oral Medicine

Contact Info

Product

Resources

About