As a result of mass incarceration and the deinstitutionalization of mental health, carceral settings in the USA are in dire need of systemic therapy. Therapists treating the incarcerated face unique challenges that therapists in traditional settings do not, like security risks, maintaining confidentiality, navigating dual relationships, and acquiring appropriate training. As such, it is imperative that carceral therapists have access to incarcerated informed clinical supervision. Yet, the literature on this is sparse. In this paper, we propose the Tadros Theory of Change, a clinical supervision framework for working with incarcerated individuals and their families. Multicultural and ethical considerations are explored.