ABSTRACT. The literature on family predictors of substance use for the general population is reviewed and compared to findings for three specific ethnic groups: black, white and Asian Americans. Rates of substance use initiation are examined in a sample of 919 urban 5th-grade students. Ethnic differences on measures of family predictors are examined and significant ethnic differences are found on several of these factors. Finally, separate regressions for black, white and Asian American youths of family factors on the variety of substances initiated examine ethnic similarities and differences in predictors. The results demonstrate significant differences by ethnicity in family management practices, involvement in family activity, sibling deviance, parental disapproval of children's drinking and family structure. The regression equations identified unique as well as common predictors of the variety of substances initiated by the end of 5th grade. Examination of both ethnic differences in the relationship between identified family risk factors and ethnic differences in the ability of these factors to predict drug use is important for prevention efforts. If ethnic groups are differentially exposed to these family risk factors and the risk factor's ability to predict drug use is the same across ethnic groups, this would suggest that prevention efforts should perhaps concentrate on those groups with the highest exposure to the risk factor. If, instead, some of the family risk factors predict drug use for one group but not for others, this would suggest that prevention efforts should address only those risk factors that are predictive for each group. This article organizes and summarizes existing literature on family factors associated with adolescent drug use that have been identified using data that include but do not distinguish etl',nic groups of color (here referred to as general studies) and compares these findings to those for three ethnic groups of color, black, white and AsianAmerican youths. This summary is important to give the reader an understanding of the degree to which findings in general studies have or have not been replicated in ethnic-
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