The aim of this Special Issue is to advance our understanding of the factors that shape the experience, well-being, and mental health of individuals on their path to creating new family forms, including adults and children, and to inform the development of policies and practices designed to promote the thriving of these families. This Special Issue contains a collection of 13 papers that shed light on a range of micro- and macro-level factors contributing to the experience and outcomes of members of new family forms from various countries, such as the UK, Israel, Italy, China, Portugal, the Netherlands, the US, and Russia. The papers extend the current knowledge on the subject from a variety of perspectives, including medical, psychological, social, and digital communications. Their findings can aid professionals supporting members of new family forms to recognize the similarities and challenges they share with their counterparts in traditional heterosexual two-parent families, as well as their unique needs and strengths. They may also encourage policymakers to promote laws and policies designed to address the cultural, legal, and institutional constraints facing these families. Based on the overall picture that emerges from this Special Issue, we suggest valuable avenues for future research.