Abstract:Escitalopram is a potent and highly selective SSRI, whose efficacy and safety in the treatment of MDD have recently been established. This study compared the efficacy and safety of escitalopram to placebo in outpatients with SAD (DSM-IV criteria) with a baseline LSAS >=70 and a CGI-S >=4. After a l-week, single-blind placebo period, patients were randomised to 12 weeks of double-blind treatment with lOmg/day escitalopram (n=181) or placebo (n=l77), with the option of having their dosage doubled after 4,6, or 8… Show more
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