Family case of Legg-Calve-Perthes disease

Protsailo, M. D.; Крицький, І. О.

doi:10.15574/ps.2019.63.104

Cited by 2 publications

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“…The morphogenesis of the knee joint is extremely complex and not fully understood. Most scientists noticed that various diseases most often manifest in this anatomical part of children [9,10]. The bone growth plates of the knee joint are one of the largest in the child's body.…”

Section: Introduction / вступmentioning

confidence: 99%

The Knee Joint Is the Achilles' Heel of a Child's Body

Protsaylo,

Dzhyvak,

Synytska

et al. 2023

EUMJ

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The study objective was to draw practicing physicians’ attention to the risk of knee joint disorders in children during intensive growth to ensure timely detection and treatment. Materials and Methods. We analyzed the results of studies on the diseases of the knee joint carried out by modern scientists over the past ten years. We also took into account the clinical observations of children receiving inpatient treatment at the regional children's hospital. The examination methods were radiography, computer tomography, magnetic resonance imaging, and ultrasound. Results and Discussion. During growth, a child's knee joint is subjected to enormous loads and is sensitive to external and internal factors. The knee joint plays a dominant role in the limb’s longitudinal growth; the growth zones grow so intensively that they can be compared to the work of a "bone nuclear reactor." The bones of the skeleton grow unevenly and intermittently. The peak height velocity is observed at 10–14 years in girls and at 13–18 years in boys; then, height velocity slows down, and after 19 years, height growth almost stops. During the period of intensive growth, bones are very sensitive to internal and external factors of shape formation (growth hormones, physiological loads, radiation, vibration, injuries, hypothermia, metabolic disorders, etc. Therefore, this part is most sensitive to various endogenous and exogenous factors, which is manifested by various dysplastic changes and diseases. Conclusions. During the intensive growth of the child, the knee joint is most vulnerable to various endogenous and exogenous negative factors, which is manifested by various diseases. Osteogenic sarcoma, fibrous cortical defect, and juvenile osteocartilaginous exostoses most often affect the weakest place of the knee joint – the metaphyses of the femur and tibia (Achilles’ heel).

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Section: Introduction / вступmentioning

confidence: 99%

The Knee Joint Is the Achilles' Heel of a Child's Body

Protsaylo,

Dzhyvak,

Synytska

et al. 2023

EUMJ

View full text Add to dashboard Cite

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Clinical Features of Connective Tissue Dysplasia, Osgood-Schlatter Disease and Multiple Cortical Disorders in a Child

Protsailo,

Fedortsiv,

Dzhyvak

et al. 2023

Wiad Lek

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The aim: To analyze scientific data on the problems of disorders of bone morphogenesis in children, in particular, non-ossifying fibroma. To analyze modern methods of diagnosis and treatment of this disease in the context of the latest scientific achievements. Materials and methods: The latest data of scientists from the world’s leading clinics describing various forms of fibrous skeletal lesions in children of differ¬ent ages were analyzed. We examined a boy with fibrous lesions of the cortical layer of the knee joint bones and a girl with a large fibrous focus of the distal femoral metaphysis, which resulted in a closed pathological bone fracture. Surgical treatment, osteosynthesis, marginal resection of the tumor, bone grafting and histological examination were conducted. Conclusions: Despite numerous studies of this disease, the etiopathogenesis of this disease has not been studied. There are no early symptoms of fibrous bone lesions in children. Diagnosis is possible only when a pathological fracture of the affected bone occurs due to extensive growth of fibrous tissue and a significant decrease in the mechanical strength of the bone. Most cases of recognition of such a disease occur accidentally when performing X-ray examinations for other reasons - bruises, sprains, arthralgias, osteochondropathy, infectious diseases, etc. It is known that boys are more mobile and require more frequent X-ray examinations for limb injuries than girls, so the likelihood of accidental detection of such changes increases significantly. Thus, long-term observations of children with fibrous bone lesions have shown that after 40 years, patients rarely developed malignant tumors - osteogenic sarcoma, fibrosarcoma, malignant fibroma of tubular bones, pelvic bones. There are no early symptoms of fibrous bone lesions in children. Recognition of such a disease occurs by chance when X-ray examinations are performed for other reasons.

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Family case of Legg-Calve-Perthes disease

Cited by 2 publications

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The Knee Joint Is the Achilles' Heel of a Child's Body

The Knee Joint Is the Achilles' Heel of a Child's Body

Clinical Features of Connective Tissue Dysplasia, Osgood-Schlatter Disease and Multiple Cortical Disorders in a Child

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