“…Another study showed that the behavior of the family toward the UHR subject modified the outcome, with “positive remarks” and “signs of affection” (parental warmth), respectively, leading to a reduction in negative symptoms and improved social functioning ( 24 ). Conversely, one study found that family therapy improved positive symptoms, but not negative symptoms or social functioning ( 25 ). Criticisms from family members are linked to high levels of cortisol, a marker of stress, in patients and especially in UHR patients ( 26 ).…”