“…Due to the long durationand due to their involvement, also they reported that the patients and their family caregivers experience health problems and burden.Several studies have reported in Iran high burden, family distress, anxiety and death anxiety, lifestyle disruption, unmet needs of the family caregivers, lack of special education, confusion, uncertainty, financial problems, lack of providing information, which is in line with our findings (Naghavi et al, 2009;TorabiParizi et al, 2018). Furthermore, similar to our study, several studies outside of Iran have reported fatigue, sleep disturbance, anxiety, depression, loss of control, decreased satisfaction, functional impairment, physical pain, financial burden, lack of knowledge and fatigue (TorabiParizi et al, 2018;Ziemba , 2016 ;Johnson et al, 2007;Parmar et al, 2014;Rose et al, 2004). In addition to, the disclosure of the disease in Iran is not culturally possibleand due to the lack of disclosure to patients and their families mental stress of caregiving is higher (TorabiParizi et al, 2018).…”