Family History Attributes and Risk Factors for Breast Cancer in Turkey

Abstract

Background: When dealing with breast cancer, early detection is closely associated with determining and closely monitoring high risk groups. The aim of this study was to determine the preventable risk factors that are specific for our country, and to understand which risk factors were most predominant. Materials and Methods: The study was planned as a case-control design. Women diagnosed with breast cancer who visited the Surgery, Obstetrics and Gynaecology, and Radiation Oncology outpatient clinics of the Izmir Dokuz Eylul University (DEU) School of Medicine were accepted as the case group. Then a control group matched for age was established among females who visited the outpatient clinics on the same days. A questionnaire prepared by the researchers was implemented using a face-to-face interview technique. The Mann-Whitney U test was used in the comparisons of the group averages, and the Pearson chi-square test in the comparisons between groups. In order to determine the dominant risk factors, binary logistical regression test was implemented. Results: A total of 138 patients, 69 cases and 69 controls, were included in the study. A significant difference can be detected between the groups in terms of BMI, smoking, breast cancer prevalence among first degree family members, presence of breast cancer among distant family members, existence of other types of cancers among family members and the age of onset of menopause (p<0.05). Logistical regression analysis revealed that the presence of breast cancer among first degree relatives increased the risk of developing breast cancer 5.7 times. Conclusions: Although some results of this study are compatible with findings in the literature, some are not. In order to determine unique risk factors, there is a clear need for large-scale studies.

Risk of Breast Cancer among Young Women and Importance of Early Screening

“…Family history of breast cancer is another established risk factor (Deirdre et al, 2002). A similar study conducted in Turkey revealed that the risk increases 5.7 times in a woman who has a first degree relative suffering from breast cancer (Gokdemir-Yazar et al, 2014). In our study, a total of 15% women reported to have a positive family history for breast cancer which is slightly less than the percentage observed among Female British University Students which was reported to be 17.2 % (Kanayo et al, 2010).…”

Awareness of Risk Factors for Cancer among Omani adults- A Community Based Study

“…It is well documented that family history of cancer increases the risk to certain types of cancer (Murff et al, 2004). For example, the presence of breast cancer among first degree relatives increased the risk of developing breast cancer 5.7 times and adults who had relatives with any types of cancer advised to adapt a healthy lifestyle to decrease the risk (Lotreane tal., 2013;Gokdemir-Yazar et al, 2014). Thus, the majority of women in western countries were able to identify that family history of breast cancer is a risk factor for breast cancer (Breslow et al, 1997).…”

Toplum Tabanlı Kanser Taraması: Hedef Topluma Ulaşmak

“…34 It has been determined that women have a greater risk of breast cancer if there is a family history of cancer. 35 In our study, 25.50% of the women had first-degree relatives cancer history, 14.20% had breast cancer in their family, and 14.60% lung cancer. Participants were also given information and resources of health literacy, not only about breast-cervix cancer but also about healthy-life styles.…”