Family history, comorbidity, smoking and other risk factors in microscopic colitis: a case–control study

Abstract

Association with a family history of microscopic colitis indicates that familial factors may be important. The association with a history of UC should be studied further as it may present new insights into the pathogenesis of microscopic colitis and UC.

Microscopic colitis and its associations with complications observed in classic inflammatory bowel disease: a systematic review

“…Rheumatic diseases were covered by four articles, osteoporosis and anemia were covered by two articles each and cutaneous diseases, eye diseases, thromboembolism and uveitis were covered by one article (Table 1). One article covered six different topics, namely anemia, cutaneous diseases, eye diseases, malignancy and rheumatic diseases [17]. Not a single article covered the topic of liver diseases.…”

“…Not a single article covered the topic of liver diseases. Two articles separated MC into CC and LC [17,18]. Four articles used other patients suffering from functional diarrhea or patients undergoing colonoscopic screening, and not healthy subjects, as controls [21,23,24,27].…”

“…Malignancy/neoplasia was covered in seven different articles [17][18][19][20][21][22][23]. Of these, four articles showed no statistically significant association between MC and malignancy/ neoplasia [17,18,20,23]. Additionally, Levy et al [23] could not show any association between MC and colonic neoplasia.…”

“…Microscopic colitis and rheumatism 129 [17,18,20,24]. Two out of four articles had separated their results into CC and LC [17,18].…”

“…Microscopic colitis and rheumatism 129 [17,18,20,24]. Two out of four articles had separated their results into CC and LC [17,18]. Roth et al [20] and Gu et al [24] concluded that there was a significant association between MC and rheumatoid arthritis (RA) (OR: 7.21; 95% CI: 3.81-13.64 and p ¼ .022, respectively).…”