Family history of cardiovascular disease as a risk factor for coronary artery disease in adult offspring

Hoseini, Kianoosh; Sadeghian, Saeed; Mahmoudian, M; Hamidian, Reza; Abbasi, Ali

doi:10.4081/monaldi.2008.427

Cited by 13 publications

(14 citation statements)

References 15 publications

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“…Meanwhile elevated resting heart rate is known as a CAD risk factor, which is in agreement with our findings (w=0.674) [51]. In the literature, the family history of CAD is a major CAD risk factor in adults [52]. This is in agreement with our findings where it had the highest GMM weight (w=1; Table 5).…”

Section: Discussionsupporting

confidence: 92%

Coronary Artery Disease Diagnosis Using Supervised Fuzzy C-Means with Differential Search Algorithm-based Generalized Minkowski Metrics

Negahbani¹,

Joulazadeh²,

Marateb³

et al. 2015

Biomed Sci Eng

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Introduction: Coronary Artery Disease (CAD), one of the leading causes of death, is narrowing the walls of the coronary arteries. Angiography is the most accurate but invasive and costly CAD diagnosis method associated with mortality. The aim of this study was to design a computer-based non-invasive CAD diagnosis system. Methods: In this work, a dataset from Cleveland clinic foundation, containing 303 patients and 20 features, was used. Supervised Fuzzy C-means (SFCM) classification was used to design a classifier for CAD diagnosis. The Generalized Minkowski Metrics (GMM) was used to handle objects containing different measurement scale features. The performance of the SFCM was assessed with/without Statistical Feature Selection (SFS). The weights of the GMM, i.e. the significance of different features, beside other classifier parameters were tuned using Differential Search Algorithm (DSA), and the validity of the proposed classifier was further investigated. The hold-out and 10-fold cross validation were used for the performance assessment. Result: The average accuracy of the base classifier (SFCM + GMM) was 79% (hold-out validation). It increased to 82% when using SFS. The average accuracy, sensitivity and specificity of the DSA-based classifier were 88%, 86% and 88%, respectively (cross-validation). Conclusion: The most important features were the number of major vessels colored by fluoroscopy, the family history of CAD, peak exercise systolic blood pressure, maximum exercise heart rate achieved, chest pain type, resting heart rate, Fasting Blood Sugar and gender. This classifier showed substantial agreement with the angiographic results. The hybrid diagnosis system is thus promising. However, it is necessary to improve its reliability. The CAD risk factors have been identified over the past several decades include abnormal levels of circulating cholesterol, hypertension, cigarette smoking, diabetes, male gender, postmenopausal state, advancing age, sedentary lifestyle, obesity, and a positive family history of premature vascular disease. Moreover, new risk factors have been emerged as elevated blood levels of homocysteine, fibrinogen, inflammation and infection, atherogenic lipoprotein phenotype, elevated levels of lipoprotein, insulin resistance syndrome, psychosocial factors and a number of genetic polymorphisms [5]. There are several diagnostic tools for CAD [6-8]. Some of the general diagnostic tests include physical examination, lab tests, Electrocardiogram (ECG), echocardiogram, stress test, electron beam computed tomography, coronary angiography and cardiac catheterization. One of the major limitations of ECG is the undiagnosed symptoms of CAD. On the other hand, another alternative invasive methodology, angiogram, is painful and discomfort to the patients. Furthermore, the above mentioned procedures take a lot of cost, time and effort [9].

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Section: Discussionsupporting

confidence: 92%

Coronary Artery Disease Diagnosis Using Supervised Fuzzy C-Means with Differential Search Algorithm-based Generalized Minkowski Metrics

Negahbani¹,

Joulazadeh²,

Marateb³

et al. 2015

Biomed Sci Eng

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“…Family history of IHD was identified in 6.4% of the patients ACS. Although, there is a debate about the role of positive family history as an independent risk factor for coronary artery disease, it was reported that, positive family history is a major risk factor for coronary artery disease which intensely predisposes to the atherosclerotic development at younger ages; therefore, these patients should be assessed and managed more intensively for other risk factors [35]. Family history of coronary heart disease (CHD) is a well-established risk factor for CHD.…”

Section: Discussionmentioning

confidence: 99%

Risk Factors Associated with Acute Coronary Syndrome in Northern Saudi Arabia

2017

JCCR

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Objective: The aim of this study was to find out the common risk factors associated with Acute Coronary Syndrome (ACS) in Northern Kingdom of Saudi Arabia (KSA).Methodology: One hundred and fifty six patients with ACS were investigated in intensive care unit (ICU), at cardiac center in King Khalid Hospital, in northern KSA, city of Hail.Results: Risk factors for ACS including; Hypertension, Ischemic Heart Disease (IHD), Smoking, Diabetes Miletus (DM), and Dyslipidemia were found in 68.6%, 34.6%, 20.5%, 59% and 83.3% of the patients, respectively. Conclusion:The most common risk factors for ACS in northern KSA (Hail region) were dyslipidemia and hypertension. These favored the urgent need for intervention and control, which lower the burden of ACS.

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“…[1][2][3][4] Meanwhile, studies have revealed that anemia is an important risk factor for CAD-related mortality and morbidity. [5][6][7] Mortality of surgical intervention for coronary artery revascularization is also associated with preoperative anemia.…”

Section: Introductionmentioning

confidence: 99%

Association between preprocedural hemoglobin level and 1-year outcome of elective percutaneous coronary intervention

Hosseini

Alemzadeh‐Ansari

Lotfi‐Tokaldany

et al. 2014

Journal of Cardiovascular Medicine

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Family history of cardiovascular disease as a risk factor for coronary artery disease in adult offspring

Abstract: These findings indicate that positive family history is a major risk factor for coronary artery disease which strongly predisposes to the atherosclerotic process at younger ages; therefore, these patients should be evaluated and managed more intensively for other risk factors.

Cited by 13 publications

References 15 publications

Coronary Artery Disease Diagnosis Using Supervised Fuzzy C-Means with Differential Search Algorithm-based Generalized Minkowski Metrics

Coronary Artery Disease Diagnosis Using Supervised Fuzzy C-Means with Differential Search Algorithm-based Generalized Minkowski Metrics

Risk Factors Associated with Acute Coronary Syndrome in Northern Saudi Arabia

Association between preprocedural hemoglobin level and 1-year outcome of elective percutaneous coronary intervention

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