Family History of Children and Adolescents with Neurocardiogenic Syncope

Vlahos, Antonios P.; Kolettis, Theofilos M.

doi:10.1007/s00246-007-9099-6

Cited by 19 publications

(12 citation statements)

References 5 publications

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“…V VS occurs in 33% to 80% of children with syncope. 624,628 Risk factors that raise suspicion of a cardiac etiology include the absence of prodromal symptoms, presence of preceding palpitations within seconds of loss of consciousness, lack of a prolonged upright posture, syncope during exercise or in response to auditory or emotional triggers, family history of SCD, abnormal physical examination, and abnormal ECG, 626,627 although the specificity is modest. 618,627,630,633 It should be remembered that children may not be able to clearly communicate specific symptoms.…”

Section: Pediatric Syncope: Recommendationsmentioning

confidence: 99%

2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society

Sheldon²,

et al. 2017

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Section: Pediatric Syncope: Recommendationsmentioning

confidence: 99%

2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society

Sheldon²,

et al. 2017

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“…I C-LD VVS evaluation, including a detailed medical history, physical examination, family history, and a 12-lead ECG, should be performed in all pediatric patients presenting with syncope. 315,618,620,[624][625][626][627][628][629][630] See Online Data Supplement 40.…”

Section: Cor Loe Recommendationsmentioning

confidence: 99%

2017 ACC/AHA/HRS guideline for the evaluation and management of patients with syncope

Shen¹,

Sheldon²,

et al. 2017

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“…Moreover, a positive family history of syncope was present in more than half (64%) of our patients. Previous studies have shared this finding and have suggested that a family history of vasovagal symptoms is of value in preventing the misdiagnosis and inappropriate initiation of antiepileptic therapy and should thus be meticulously sought [11,13,14].…”

Section: Discussionmentioning

confidence: 69%

“…The third most frequent event was vasovagal syncope (12%). The importance of history-taking in distinguishing syncope from seizures has been addressed by a number of studies demonstrating an incomplete history as the major cause for misdiagnosis [4,[10][11][12].…”

Section: Discussionmentioning

confidence: 99%

“…Misdiagnosed as Received non-epileptic disorder epilepsy n (%) antiepileptics n (%) Breath-holding spell (37) 11 (30) 9 (24) Hyperekplexia (5) 5 (100%) 5 (100%) Jitteriness or possible atypical hyperekplexia (15) 11 (73%) 11 (73%) Vasovagal attack (12) 0 0 Pseudoseizures (11) 11 (100) 11 (100) Gastroesophageal reflux (10) 2 (20) 2 (20) Masturbation 31 (33) 1 (33) Tic 21 (50) 1 (50) Head nodding (2) 0 0 Paroxysmal torticollis (1) 0 0 Migraine 11 (100) 1 (100) Vitamin B12 deficiency tremor 11 (100) 1 (100)…”

Section: Number Of Patients For Each Paroxysmalmentioning

confidence: 99%

See 1 more Smart Citation

Misdiagnosis of paroxysmal non-epileptic disorders in children

Masri

Shanab

2015

J Pediatr Neurol

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Paroxysmal non-epileptic disorders (PNEDs) are often misdiagnosed as epilepsy. This study describes cases of misdiagnosed PNEDs. In addition, it identifies aspects of the clinical assessment that may assist in reaching a correct diagnosis. A total of 100 patients (58 boys and 42 girls) were included. Misdiagnosed PNEDs included: breath-holding spells (37%); excessive jitteriness and/or atypical hyperekplexia (15%); vasovagal attack (12%); psychogenic seizures (11%); gastroesophageal reflux (10%); hyperekplexia (5%); masturbation (3%); head nodding (2%); tic (2%); paroxysmal torticollis (1%); migraine (1%); vitamin B12 deficiency-induced tremor (1%). Forty-four (44%) patients were misdiagnosed with epilepsy and parents presented for a second opinion, while 56 (56%) patients were referred with a suspicion of epilepsy. Forty-two (42%) patients received antiepileptic treatment before presenting to us. History emerged as the most helpful diagnostic tool. Examination was only useful in hyperekplexia, while mobile phone video camera emerged as a potentially useful but underutilized diagnostic tool and were present in 85% of the patients. PNEDs are often misdiagnosed as epilepsy. Elements that were helpful in making a correct diagnosis included history, examination, and witnessing the attack in clinic or on mobile phones.

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Family History of Children and Adolescents with Neurocardiogenic Syncope

Cited by 19 publications

References 5 publications

2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society

2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society

2017 ACC/AHA/HRS guideline for the evaluation and management of patients with syncope

Misdiagnosis of paroxysmal non-epileptic disorders in children

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