Family history of psoriasis and age at disease onset in Italian patients with psoriasis

Altobelli, Emma; Petrocelli, Reimondo; Marziliano, Ciro; Fargnoli, Maria Concetta; Maccarone, Mara; Chimenti, Sergio; Peris, Ketty

doi:10.1111/j.1365-2133.2007.07906.x

Cited by 27 publications

(27 citation statements)

References 7 publications

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“…Although there are some studies2526 that family history is associated with early onset age, but it was difficult to find a study to explain a relationship between family history and disease severity. However, López-Estebaranz et al27 recently presented that the severity of psoriasis was not affected by the presence of a family history.…”

Section: Discussionmentioning

confidence: 99%

The Clinical Profile of Patients with Psoriasis in Korea: A Nationwide Cross-Sectional Study (EPI-PSODE)

et al. 2017

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BackgroundPsoriasis is an immune-mediated, chronic inflammatory disease affecting multiple aspects of patients' lives. Its epidemiology varies regionally; however, nationwide epidemiologic data on psoriasis depicting profile of Korean patients has not been available to date.ObjectiveTo understand nationwide epidemiologic characteristics and clinical features of adult patients with psoriasis visited university hospitals in Korea.MethodsThis multicenter, non-interventional, cross-sectional study recruited 1,278 adult patients with psoriasis across 25 centers in Korea in 2013. Various clinical data including PASI, BSA, DLQI, SF-36 and PASE were collected.ResultsA total of 1,260 patients completed the study (male:female=1.47:1). The mean age was 47.0 years with a distribution mostly in the 50s (24.9%). Early onset (<40 years) of psoriasis accounted for 53.9% of patients. The mean disease duration was 109.2 months; mean body mass index was 23.9 kg/m2; and 12.7% of patients had a family history of psoriasis. Plaque and guttate types of psoriasis accounted for 85.8% and 8.4%, respectively. Patients with PASI ≥10 accounted for 24.9%; patients with body surface area ≥10 were 45.9%. Patients with DLQI ≥6 accounted for 78.8%. Between PASI <10 and PASI ≥10 groups, significant difference was noted in age at diagnosis, disease duration, blood pressure, waist circumference of female, and treatment experiences with phototherapy, systemic agents, and biologics.ConclusionThis was the first nationwide epidemiologic study of patients with psoriasis in Korea and provides an overview of the epidemiologic characteristics and clinical profiles of this patient population.

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Section: Discussionmentioning

confidence: 99%

The Clinical Profile of Patients with Psoriasis in Korea: A Nationwide Cross-Sectional Study (EPI-PSODE)

et al. 2017

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“…Approximately 30% of children with psoriasis have an affected first‐degree relative, and a positive family history can predict early disease onset . Psoriasis appears earlier in girls, and some studies also report a slight female bias in overall incidence .…”

Section: Epidemiology and Natural History Of Diseasementioning

confidence: 99%

Pediatric psoriasis: Evolving perspectives

Eichenfield

Paller

Tom

et al. 2018

Pediatric Dermatology

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“…Psoriasis is a frequent and burdensome disease in children and adults 1,2 . Family history of psoriasis predicts early disease onset 3,4 . Among children (0–18 years) the median age at onset of psoriasis was found to be between 7 and 10 years 5–8 .…”

mentioning

confidence: 99%