Fan-shaped hepatic parenchymal damage after ethanol injection therapy for hepatocellular carcinoma: MRI appearances

Fujita, Takeshi; Honjo, Kazumitsu; Ito, Katsuyoshi; Arita, Tomohiro; Koike, Shinji; Takano, Koichi; Tamura, Shigeyuki; Matsumoto, Tsuneo; Matsunaga, Naofumi

doi:10.1007/s002619900440

Cited by 6 publications

(2 citation statements)

References 17 publications

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“…This postprocedural sign is likely to be a transient reaction of normal tissue to thermal damage, as it is detectable also in other procedures inducing tissue heating. On histologic specimen, this finding has been explained with a massive sinusoidal dilatation at the boundary between the coagulated area and the surrounding normal tissue, determining a peripheral granulation tissue and fibrosis after treatment [ 73 , 74 ]. After treatment, an increase of arterial blood flow may occur at the margin of the treated area, leading to hepatic hypoperfusion during the arterial phase as a result of inflammation changes caused by microwaves irradiation as well as radiofrequency thermal ablation [ 67 , 75 ].…”

Section: Appearance Of Treated Hccmentioning

confidence: 99%

CT Appearance of Hepatocellular Carcinoma after Locoregional Treatments: A Comprehensive Review

Marín

Cappabianca

Serra

et al. 2015

Gastroenterology Research and Practice

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Hepatocellular carcinoma (HCC) is a major health problem worldwide, affecting more than 600,000 new patients per year. Curative treatments are available in a small percentage of patients, while most of them present in stages requiring locoregional treatments such as thermoablation, transarterial chemoembolization, and/or radioembolization. These therapies result in specific imaging features that the general radiologist has to be aware of in order to assess the response to treatment and to correctly manage the follow-up of treated patients. Multiphasic helical computed tomography has become a popular imaging modality for detecting hypervascular tumors and characterizing liver lesions. On this basis, many staging and diagnostic systems have been proposed for evaluating response to all different existing strategies. Radiofrequencies and microwaves generate thermoablation of tumors, and transarterial chemoembolization exploits the double effect of the locoregional administration of drugs and embolizing particles. Eventually radioembolization uses a beta-emitting isotope to induce necrosis. Therefore, the aim of this comprehensive review is to analyze and compare CT imaging appearance of HCC after various locoregional treatments, with regard to specific indications for all possible procedures.

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Section: Appearance Of Treated Hccmentioning

confidence: 99%

CT Appearance of Hepatocellular Carcinoma after Locoregional Treatments: A Comprehensive Review

Marín

Cappabianca

Serra

et al. 2015

Gastroenterology Research and Practice

View full text Add to dashboard Cite

show abstract

“…Lesions appear hypointense on T2-weighted images if necrosis is complete, whereas residual tumour appears as a high-intensity signal 159,160 . Serum AFP is also useful, but only if pretreatment levels are raised 152,161 .…”

Section: Assessment Of Technique and Follow-upmentioning

confidence: 99%