Fanconi’s syndrome and distal (Type 1) renal tubular acidosis in a patient with primary Sjögren’s syndrome with monoclonal gammopathy of undetermined significance

Myeloma-related Kidney Disease

“…Distal tubular dysfunction including distal renal tubular acidosis and nephrogenic diabetes insipidus can rarely occur with the proximal tubular dysfunction. [78][79][80] The mechanism for this is not well understood, and other disease processes may be involved. 78 The most common pattern seen on kidney biopsy is patchy tubular injury.…”

Renal Involvement in Primary Sjögren's Syndrome

“…Tubulointerstitial nephritis (TIN) remains the most common presentation of renal involvement in pSS and CD4/CD8 T cell subsets are reported to predominate (27,30). This is often characterized by a distal (type I) renal tubular acidosis (RTA) and less commonly proximal (type II) RTA (Fanconi syndrome) (11,(31)(32)(33). GN is thought to be a rare occurrence, with only case reports available in the literature (10,(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23), and tends to be a late development (34) in the course of the disease.…”

Acute Kidney Injury in a Patient with Polyarteritis Nodosa and Multiple Myeloma

“…Moreover, as described above, the patient's urine was negative for BJP and no cryoglobulinemia was detected. On the other hand, there are a few reports showing monoclonal gammopathyassociated renal impairment without paraprotein deposition in either the glomeruli or tubules (18)(19)(20)(21)(22)(23)(24). In a case series of nine patients, Ramos et al concluded that the presence of paraproteins may lead to secondary renal impairment, and they reported four patients who exhibited a worsening of the renal function and required dialysis during a mean follow-up period of 2.4±4.3 years (25).…”