Sweet potato is a food security crop with ease of production and ability to produce relatively good yields even on marginal soils. Despite these potentials, its yields have drastically reduced in recent years relative to what it used to be in the 60's and 90's. This is not unconnected with climate change, among other factors. This study therefore examines the perceptions of sweet potato farming households on climate change, the strategies employed and factors influencing their adaptation to its effects. Data were collected from 170 sweet potato farming households in Kwara State, Nigeria and analyzed with descriptive statistics, index ranking and logistic regression. Results showed that most of the farmers were aware of climate change and use different strategies to combat its deleterious effects. Factors that positively influence the farmers' adaptation status were educational status, farming experience, farm size and access to agricultural extension services while age had a negative influence on their adaptation status (at p < 0.05). Therefore, policies that will promote literacy and access to extension services among farming households and also encourage young people to practise sweet potato farming should be put in place.