Farnesol potentiates photodynamic inactivation of Staphylococcus aureus with the use of red light-activated porphyrin TMPyP

Vasodilation promoted by (E,E)-farnesol involving ion channels in human umbilical arteries

“…In this context, farnesol (IUPAC: 3,7,11-trimethyl-2,6,10-dodecatrien-1-ol), an acyclic sesquiterpene alcohol (C 15 ) of phytochemical occurrence present in many essential oils of medicinal plants, such as citronella, neroli, lemon grass and rose [ 2 ], is a ubiquitous molecule in nature, and is also an endogenous byproduct (and modulator) of the MEV/cholesterol biosynthetic pathway in mammalian cells, and three possible sources have been previously described for these: (1) interconversion with farnesyl pyrophosphate (FPP); (2) degradation of prenylated proteins; (3) dietary or pharmaceutical [ [3] , [4] , [5] , [6] ].…”