Fasciola hepatica: Development of tegument during migration in mouse

Bennett, C.E.; Threadgold, L.T.

doi:10.1016/0014-4894(75)90036-3

Cited by 107 publications

(60 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the case of Clonorchis sinensis, for example, it was reported that larval flukes which just excysted in the duodenum had double or triple-pointed tegumental spines at the anterior half of the body, but spines gradually disappeared as the worms grew to be adults (Fujino et al, 1979;Lee et al, 1982). On the contrary, for the larval flukes of Fasciola hepatica, tegumental spines having single tip metamorphose into multipointed ones just prior to entry into the bile duct (Bennett and Threadgold, 1975). The conversion of simple shaped spines into serrated ones during the parasite development is also known in Neodiplostomum seoulense (Lee et al, 1985) and Paragonimus iloktsuenensis (Lee et al, 1989).…”

Section: � �mentioning

confidence: 97%

“…Considering the fact that the developmental changes in spine differentiation are required to help flukes adapt the microenvironment in the host (Bennett and Threadgold, 1975), characteristics in host-parasite relationships may be different between M. takahashii and M. yokogawai. More active and remarkable differentiation of tegumental spines in M. takahashii during their development may be related to the differences in taking microhabitats in the host intestine, invasiveness into the host mucosa and pathogenicity, and possibly, capability of evasion from the host immunity.…”

Section: � �mentioning

confidence: 99%

See 1 more Smart Citation

Surface ultrastructure of Metagonimus takahashii metacercariae and adults

et al. 2000

View full text Add to dashboard Cite

Section: � �mentioning

confidence: 97%

Section: � �mentioning

confidence: 99%

Surface ultrastructure of Metagonimus takahashii metacercariae and adults

et al. 2000

View full text Add to dashboard Cite

“…hepatica is able to replace the surface glycocalyx during its migration through the liver parenchyma, and these changes continue after entry into the bile duct (4-5 w.p.i.) (Bennett and Threadgold 1975). When fasciolae are localised in the bile ducts, ES products are released, being eliminated via the faeces and detected by means of a sandwich-ELISA.…”

Section: Discussionmentioning

confidence: 99%

Time-course analysis of coproantigens in rats infected and challenged with Fasciola hepatica

et al. 2002

View full text Add to dashboard Cite

The influence of a challenge infection during an acute or chronic primary infection on Fasciola hepatica-coproantigen kinetics was established in rats. Egg-output and IgG humoral responses were also established. Two primary-infected groups were reinfected at different periods, one 4 weeks after primary infection (w.p.i.) (acute phase) and the other 11 w.p.i. (chronic phase). Another group remained without reinfection as a control. Coproantigens were first detected in the group challenged on acute fascioliasis. The highest values of coproantigens were recorded in the group reinfected during acute fascioliasis and the lowest in the group challenged during chronic fascioliasis. The IgG responses to F. hepatica excretory/secretory antigens increased after reinfection. Neither the egg output nor the parasitic burden were significantly different among the three infected groups. Our results indicate that the time of challenge affects the kinetics of coproantigens. Thus, challenge during acute fascioliasis favours the migration of the juvenile flukes from the primary infection to the bile ducts, and is responsible for the earlier presence of coproantigens in these animals. The possible relationship between coproantigen detection and T1 and T2 tegumentary antigens is discussed.

show abstract

“…Such changes have been documented in life-cycle stages of Fasciola hepatica by Southgate (1970) and Bennett & Threadgold (1975), in Schistosoma mansoni by Hockley & McLaren (1973), Basch & DiConza (1974) and Voge, Price & Bruckner (1978), and in Mesorchis denticulatus by Keie (1987). In nematodes, developmentally related changes in cuticular morphology have been described in Onchocerca volvulus by Martinez-Palomo (1978), in Dirofilaria immitis by Lichtenfels, Pilitt & Wergin (1987), and in Trichinella spiralis by Lee & Wright (1985).…”

Section: Morphological Factors Important In Determining the Relative mentioning

confidence: 96%

The relative roles of the intestines and external surfaces in the nutrition of monogeneans, digeneans and nematodes

Pappas

1988

Parasitology

View full text Add to dashboard Cite

Several major groups of parasitic helminths (Monogenea, Digenea and Nematoda) possess two surfaces that are potentially absorptive in nature. These are an external surface, a tegument in the platyhelminths and cuticle in the nematodes, and the intestine. This paper discusses the relative contributions of these absorptive surfaces in the nutrition of these parasitic helminths. There are many factors that determine the availability of, and a parasite's ability to absorb nutrients via either of these surfaces, and this review discusses individually some of the more important morphological, physiological and environmental factors affecting the potential nutritional roles of these surfaces. It is clear from such a summary of previous studies that the intestines and teguments (cuticles) of helminth parasites can each serve an important nutritional role. However, insufficient data make it impossible at this time to determine the relative nutritional roles of these surfaces in any single parasitic helminth.

show abstract

Fasciola hepatica: Development of tegument during migration in mouse

Cited by 107 publications

References 18 publications

Surface ultrastructure of Metagonimus takahashii metacercariae and adults

Surface ultrastructure of Metagonimus takahashii metacercariae and adults

Time-course analysis of coproantigens in rats infected and challenged with Fasciola hepatica

The relative roles of the intestines and external surfaces in the nutrition of monogeneans, digeneans and nematodes

Contact Info

Product

Resources

About