Fast, compact and label-free electrical detection of live and dead single cells

Broadband Electrical Detection of Individual Biological Cells

“…This paper expands on [4] mainly by presenting detailed data and analysis at higher frequencies (gigahertz versus megahertz) to prove that the unique combination of these approaches can be reproducibly sensitive to single cells of different types.…”

“…Recently, to resolve the dilemma encountered by Coulter counters and to evolve a general-purpose electrical detection technique, we used [4] broadband microwave measurement to overcome electrode polarization, ac dielectrophoresis to precisely place cells between narrowly spaced electrodes for maximum cell-to-sample volume ratio, and relatively wide microfluidic channels to prevent cell clogging. This paper expands on [4] mainly by presenting detailed data and analysis at higher frequencies (gigahertz versus megahertz) to prove that the unique combination of these approaches can be reproducibly sensitive to single cells of different types.…”