The operating conditions of the production process significantly influence the resulting dimensional and form accuracy of the workpiece. The operating conditions include the position of the workpiece location, with internal and external heat sources influenced not only by the machine location but also by its operation. In addition, there are the cutting conditions and the feed rate requirements of CNC machine tools. These changes, such as workpiece position, feed rates, and machine heat load, are further reflected in the ability of the machine to run at the position required and interpolate within the given tolerances of circularity. For the accuracy and repeatability of positioning, the machine was set up according to ISO 230-2 and for the circular interpolation tests according to ISO 230-4. The obtained results show the importance of attention to the appropriate setting of the operating conditions of the production process, where the knowledge of the geometric accuracy of the CNC machine tool in its working space can systematically increase the manufacturing accuracy itself or be another tool suitable for predicting the dimensional and form accuracy of workpieces.