Fast emulsion droplet sizing using NMR self-diffusion measurements

Hollingsworth, Kieren G.; Sederman, Andrew J.; Buckley, Craig; Gladden, Lynn F.; Johns, M.L.

doi:10.1016/j.jcis.2004.02.074

Cited by 51 publications

(23 citation statements)

References 12 publications

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“…This droplet size distribution measurement was made using fast Difftrain PFG sequence [28] using the following experimental parameters: δ = 2 ms, 1 = 12.8 ms, inc = 65 ms, g = 10 G/cm. …”

Section: Experiments C: Multiple Drop Migration In Couette Flowmentioning

confidence: 99%

Droplet migration in emulsion systems measured using MR methods

Hollingsworth

Johns

2006

Journal of Colloid and Interface Science

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“…This droplet size distribution measurement was made using fast Difftrain PFG sequence [28] using the following experimental parameters: δ = 2 ms, 1 = 12.8 ms, inc = 65 ms, g = 10 G/cm. …”

Section: Experiments C: Multiple Drop Migration In Couette Flowmentioning

confidence: 99%

Droplet migration in emulsion systems measured using MR methods

Hollingsworth

Johns

2006

Journal of Colloid and Interface Science

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“…When the size distribution is introduced, the signal decay, plotted as a function of the b-value ͑where b = 4 2 ͉q 2 ͉t d ͒ becomes nonmonoexponential, 48 and is often modeled by a biexponential decay. Although sophisticated methods have been proposed to reconstruct the structural information in samples characterized by size distributions, 24,43,44,49,50 it would be very desirable to infer such information directly from the E͑q͒ plots. The double-PFG ͑d-PFG͒ method, first proposed by Cory et al 51 in 1990, and initially used for flow-related phenomena, 52 suppression of convection artifacts, 53 and twodimensional diffusion-diffusion correlation spectroscopy, 54 has lately gained increasing attention due to its apparent ability to recover microstructural information that is inherently lost or absent in s-PFG methods such as microscopic anisotropy in macroscopically isotropic samples.…”

mentioning

confidence: 99%

Detecting diffusion-diffraction patterns in size distribution phantoms using double-pulsed field gradient NMR: Theory and experiments

Shemesh

Özarslan

Basser

et al. 2010

The Journal of Chemical Physics

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NMR observable nuclei undergoing restricted diffusion within confining pores are important reporters for microstructural features of porous media including, inter-alia, biological tissues, emulsions and rocks. Diffusion NMR, and especially the single-pulsed field gradient ͑s-PFG͒ methodology, is one of the most important noninvasive tools for studying such opaque samples, enabling extraction of important microstructural information from diffusion-diffraction phenomena. However, when the pores are not monodisperse and are characterized by a size distribution, the diffusion-diffraction patterns disappear from the signal decay, and the relevant microstructural information is mostly lost. A recent theoretical study predicted that the diffusion-diffraction patterns in double-PFG ͑d-PFG͒ experiments have unique characteristics, such as zero-crossings, that make them more robust with respect to size distributions. In this study, we theoretically compared the signal decay arising from diffusion in isolated cylindrical pores characterized by lognormal size distributions in both s-PFG and d-PFG methodologies using a recently presented general framework for treating diffusion in NMR experiments. We showed the gradual loss of diffusion-diffraction patterns in broadening size distributions in s-PFG and the robustness of the zero-crossings in d-PFG even for very large standard deviations of the size distribution. We then performed s-PFG and d-PFG experiments on well-controlled size distribution phantoms in which the ground-truth is well-known a priori. We showed that the microstructural information, as manifested in the diffusion-diffraction patterns, is lost in the s-PFG experiments, whereas in d-PFG experiments the zero-crossings of the signal persist from which relevant microstructural information can be extracted. This study provides a proof of concept that d-PFG may be useful in obtaining important microstructural features in samples characterized by size distributions.

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“…A real emulsion will contain a distribution of droplet sizes and so the signal attenuation will be a volume weighted average that can be described by 12] where P(a) is the probability of finding a droplet of radius a expressed as a number distribution. Determining P(a) is an ill-posed problem that can be solved using regularization techniques as demonstrated by Hollingsworth and Johns (34).…”

Section: Droplet Sizingmentioning

confidence: 99%

“…In all cases the two techniques provide equivalent results, although only the Difftrain data can be acquired during in-situ drying. lets that can be accurately determined using Difftrain (12). These limits are dictated by the diffusion coefficient of the emulsified liquid and the observation time in the Difftrain measurement such that…”

Section: Droplet Sizingmentioning

confidence: 99%

“…Difftrain was proposed originally as a single-shot method for diffusion ordered spectroscopy (DOSY) measurements (11), although it has not as yet, to the best of our knowledge, been utilized by the NMR spectroscopy community. However, it has been employed in recent years for rapid materials analysis including droplet sizing (12) and microstructural characterization (13).…”

Section: Introductionmentioning

confidence: 99%

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Rapid measurements of diffusion using PFG: Developments and applications of the Difftrain pulse sequence

Mitchell

Johns

2009

Concepts Magnetic Resonance

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Pulsed-field gradient (PFG) nuclear magnetic resonance (NMR) is one of the few experimental techniques that can determine directly mean square molecular displacements, allowing self-diffusion coefficient of liquids to be derived. PFG measurements are used commonly for diffusion, flow, and microstructure characterization. However, these conventional PFG experiments are often time consuming, requiring the gradient strength or observation time to be incremented independently. Here we discuss how the rapid Difftrain pulse sequence has proved invaluable in the study of time sensitive systems by allowing multiple observation times to be probed in a single scan. Difftrain has been applied successfully to the study of emulsions, surfactant solutions, bead packs, and permeable rock cores. We discuss various implementations of the Difftrain pulse sequence, suggest suitable phase cycles, and review the applications to date.

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Fast emulsion droplet sizing using NMR self-diffusion measurements

Cited by 51 publications

References 12 publications

Droplet migration in emulsion systems measured using MR methods

Droplet migration in emulsion systems measured using MR methods

Detecting diffusion-diffraction patterns in size distribution phantoms using double-pulsed field gradient NMR: Theory and experiments

Rapid measurements of diffusion using PFG: Developments and applications of the Difftrain pulse sequence

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