Fast preparation of a highly efficient organic monolith via photo-initiated thiol-ene click polymerization for capillary liquid chromatography

Chen, Lianfang; Ou, Junjie; Liu, Zhongshan; Lin, Hui; Wang, Hongwei; Dong, Jing; Zou, Hanfa

doi:10.1016/j.chroma.2015.03.054

Cited by 48 publications

(27 citation statements)

References 48 publications

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“…According to element analysis, there was 5.8% sulfur in monolith POSSepoxy-PTM, while the content of sulfur is 8.7% in theory. It may be ascribed that some oligomers were produced when the monolith was prepared [26,27].…”

Section: Characterization Of Monoliths Poss-epoxy-ptm and Poss-epoxy-mentioning

confidence: 97%

Preparation of well-controlled three-dimensional skeletal hybrid monoliths via thiol–epoxy click polymerization for highly efficient separation of small molecules in capillary liquid chromatography

Lin

Chen

et al. 2015

Journal of Chromatography A

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Section: Characterization Of Monoliths Poss-epoxy-ptm and Poss-epoxy-mentioning

confidence: 97%

Preparation of well-controlled three-dimensional skeletal hybrid monoliths via thiol–epoxy click polymerization for highly efficient separation of small molecules in capillary liquid chromatography

Lin

Chen

et al. 2015

Journal of Chromatography A

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Section: Basic Strategy For Designing Monolithic Materialsmentioning

confidence: 99%

“…These features inspired researchers to fabricate highly crosslinking monolith via thiol‐based polymerization reaction. Our group prepared two kinds of polymeric monoliths within the confinement of UV‐transparent fused‐silica capillaries via thiol–ene/yne click polymerization reaction under the irradiation of ultraviolet light. The first polymeric monolith was polymerized via thiol–ene polymerization by irradiation at 365 nm for 10 min using pentaerythriol tetra(3‐mercaptopropionate) (PTMP) and 1,2,4‐trivinylcyclohexane as precursors (Table and Figure ).…”

Section: Basic Strategy For Designing Monolithic Materialsmentioning

confidence: 99%

Challenges and Advances in the Fabrication of Monolithic Bioseparation Materials and their Applications in Proteomics Research

Wang

et al. 2019

Advanced Materials

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High‐performance liquid chromatography integrated with tandem mass spectrometry (HPLC–MS/MS) has become a powerful technique for proteomics research. Its performance heavily depends on the separation efficiency of HPLC, which in turn depends on the chromatographic material. As the “heart” of the HPLC system, the chromatographic material is required to achieve excellent column efficiency and fast analysis. Monolithic materials, fabricated as continuous supports with interconnected skeletal structure and flow‐through pores, are regarded as an alternative to particle‐packed columns. Such materials are featured with easy preparation, fast mass transfer, high porosity, low back pressure, and miniaturization, and are next‐generation separation materials for high‐throughput proteins and peptides analysis. Herein, the recent progress regarding the fabrication of various monolithic materials is reviewed. Special emphasis is placed on studies of the fabrication of monolithic capillary columns and their applications in separation of biomolecules by capillary liquid chromatography (cLC). The applications of monolithic materials in the digestion, enrichment, and separation of phosphopeptides and glycopeptides from biological samples are also considered. Finally, advances in comprehensive 2D HPLC separations using monolithic columns are also shown.

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“…Die einfache Herstellung derartiger Säulen ist ein großer Vorteil und ein Beispiel für die nützliche Verwendung verschiedener Thiol‐Kupplungen, wie durch die Studien von Zou und Mitarbeitern demonstriert wurde. Unter Anwendung verschiedener Thiol‐Kupplungen, wie Thiol‐Epoxy‐Reaktionen, Thiol‐Acrylat‐Reaktionen, Thiol‐Michael‐Additionen, photoinitiierter Thiol‐En‐Reaktionen und photoinitiierter Thiol‐In‐Reaktionen, entwickelten Zou und Mitarbeiter HPMCs mit hoher Säuleneffizienz (Abbildung ). Die HPMCs wiesen jeweils eine erhebliche chemische, thermische und mechanische Beständigkeit auf, was außerdem ihre Praxistauglichkeit als Chromatographiesäulen demonstriert.…”

Section: Thiol‐kupplungenunclassified

Schwefel in der modernen Materialwissenschaft

Boyd

2016

Angewandte Chemie

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Schwefel ist eines der häufigsten Elemente im Universum, fällt als Hauptnebenprodukt bei der Erdölraffination an und stellt ein häufiges Reaktionszentrum in biologischen Systemen dar. Die Forschung über Schwefel ist daher breit gefächert und hat große Relevanz und Auswirkungen auf unser tägliches Leben. So hat das Interesse an schwefelbasierten Reaktionen in den letzten zehn Jahren eine deutliche Wiederbelebung erfahren. Weitere relevante Themengebiete sind Forschungen zur Verbesserung von Energieeffizienzen, umweltfreundliche Anwendungen für Abfallprodukte der Erdölraffination, Polymere mit besonderen optischen und mechanischen Eigenschaften sowie Materialien für biologische Anwendungen. Dieser Aufsatz stellt einige der neuesten Anwendungen von Schwefel und schwefelbasierten Reaktionen für die Herstellung von Materialien für den Energiebereich, Umweltschutz und andere praktische Anwendungen vor.

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Fast preparation of a highly efficient organic monolith via photo-initiated thiol-ene click polymerization for capillary liquid chromatography

Cited by 48 publications

References 48 publications

Preparation of well-controlled three-dimensional skeletal hybrid monoliths via thiol–epoxy click polymerization for highly efficient separation of small molecules in capillary liquid chromatography

Preparation of well-controlled three-dimensional skeletal hybrid monoliths via thiol–epoxy click polymerization for highly efficient separation of small molecules in capillary liquid chromatography

Challenges and Advances in the Fabrication of Monolithic Bioseparation Materials and their Applications in Proteomics Research

Schwefel in der modernen Materialwissenschaft

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