Fast Radiochemical Separation and γ Spectroscopy of Short-lived Thallium Isotopes

Abstract

A method for continuous separation and measurements of shortlived thallium isotopes is described. The Bi parent nuclides were fixed as anionic complexes B1CI4 on a Dowex 1-X8 column and the daughters Tl + were continuously eluted with a reducing solution and fixed on a Ni hexacyanoferrate(II)ion exchanger column, y-spectra of radiochemically separated 209 T1 (T ll2 = 2.2 min) and 208 T1 (T 1/2 = 3.05 min) nuclides were recorded with high efficiency HPGe coaxial detectors. Eleven y-transitions were measured in the /J-decay of 209 T1, of which 8 are observed for the first time. The new value of the 209 T1 half-life is T lj2 = (2.161 ±0.007) min. The 209 Pb level scheme was built and 4 new excited levels were suggested to be fed in the 209 T1 jS-decay at 2315.5, 3069.6, 3361.9 and 3389.1 keV.

An Improved Generator for the Production of 213Bi from 225Ac

“…The 225 Ac can be separated from 225 Ra with Dowex 50W-X8 cation exchange resin [13,14], however, this chromatography is inconveniently performed at 60 °C or 80°C. Also, we found the yield of 225 Ac by this method to be relatively poor.…”

225Ac/213Bi radionuclide generators for the separation of 213Bi towards clinical demands

“…High crosslinking degrees typically have a better stability towards radiation. 36,48,134 Dowex 50W-X8, a spherical-shaped strong cation exchange resin used in direct generators, has been reported by Samad et al and Geerlings et al 26,118 In these studies, 225 Ac (in a 1 M HNO 3 or 2 M HCl solution) was adsorbed onto the Dowex 50W-X8 column, while 213 Bi was eluted as BiCi 4…”

“…38,111 For example, Ac 3+ ions are adsorbed onto the cation exchange resin by cation exchange, while the Bi-halide complexes are adsorbed onto the anion exchange resins via the anion exchange. 26,38,111,118 Surface complexation is a crucial adsorption mechanism involving inner-and outer-sphere complexation (Fig. 7c).…”

“…− or Bi 2 Cl 8 2− by using a 0.5-2 M HCl solution as the eluent. 26,118 However, they did not provide any information regarding the yield and purity of 213 Bi. Guseva and Dogadkin used the same column materials and showed a large difference in adsorption capacity between Ac 3+ and Bi 3+ (in 0.25 M HCl), due to the formation of Bi-halide complexes (Fig.…”

The Development of the α-Particle Emitting Radionuclides 212Bi and 213Bi, and Their Decay Chain Related Radionuclides, for Therapeutic Applications

“…evaluated this generator using lower acid molarity for improved compatibility with antibody labeling, which resulted in decreased 213 Bi yield . El Samad et al also reported use of a similar 213 Bi/ 225 Ac generator, but with the 225 Ac initially extracted from 233 U by two strong anion-exchange columns (Dowex 1X8). Since their objective was a study of 209 Tl, only low-level generators were described.…”