A passive wireless impedance-loaded orthogonal frequency-coded (OFC) surface acoustic wave (SAW) sensor for wireless sensor networks was proposed in this paper. One of the chips on OFC SAW tag is connected to an external sensor, which could cause a phase shift in the time response of the corresponding part on the SAW device. The phase shift corresponds to the sensed quantity, which could be temperature, strain, vibration, pressure, etc. The OFC SAW tag is isolated by a proper package from the direct effect of the measurand on the device’s response which could avoid the multiple measurands coupling. The simultaneous work of multiple sensors is guaranteed by orthogonal frequency coding. By processing the response based on an extended matched filter algorithm, sensing information of the specific coded OFC device can be extracted from the superimposed response of multiple independent encoded sensors. Compared to previous methods, the proposed method can produce a more flexible passive (battery-free) wireless sensor suitable for large-scale wireless sensor networks. Simulation and experimental results demonstrate the effectiveness of the sensor.