Fasting blood glucose and insulin sensitivity are unaffected by HAART duration in Cameroonians receiving first-line antiretroviral treatment

Ekali, Loni G.; Johnstone, L.K.; Echouffo‐Tcheugui, Justin B.; Kouanfack, Charles; Dehayem, Mesmin; Fézeu, Léopold; Nouthe, Brice; Hayes, Louise; Unwin, Nigel; Sobngwi, Eugène

doi:10.1016/j.diabet.2012.08.012

Cited by 28 publications

(37 citation statements)

References 28 publications

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“…This observation corroborates with previous studies of Lichtenstein et al (2010), PefuraYone et al (2011), Ekali et al (2013), Muhammad et al (2013) and Njelekela et al (2016), which revealed a higher incidence of hypertension in patients on cART. Contrarily, the findings of other studies of Agrawal et al (2015) indicated no disparity in the prevalence of hypertension between patients on cART and cARTnaïve patients.…”

Section: Resultssupporting

confidence: 83%

Hypertension and Related Risk Factors Among Clients on Combined Antiretroviral Therapy in Nigeria

Bello

Ojieabu

2018

Bangla Pharma J

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Hypertension is a major challenge in human immunodeficiency virus (HIV) infected people globally. A prospective, cross-sectional study comprising two hundred and eighteen HIV-infected patients was conducted in Antiretroviral Therapy Clinic of General Hospital, Offa between November 2015 and December, 2016. Patients' blood pressure was evaluated using Omron automated blood pressure monitor following standard procedures. Dual weight and height balance was utilized to measure the weight and height of the subjects. Hypertension incidence among patients receiving combined antiretroviral therapy (cART) was 34%, while those that were yet to start cART was 9.6 %. In HIVinfected women on cART, occurrence of hypertension was high (75.5%) as compared to men (24.5%). The hypertension pervasiveness in HIV-infected patients on cART was 75.5% in women and 24.5% in men. Risk factors that were markedly linked with hypertension among patients on cART include body mass index (OR: 3.29,95% CI:1.21-2.27; p< 0.050), sedentary lifestyle (OR: 1.63, 95% CI:1.20-5.38; p < 0.043), age (OR: 2.17, 95% CI: 1.22-2.33; p< 0.004) and gender (OR: 1.63, 95% CI: 0.85-2.41; p < 0.037). Patients on cART were found to have higher hypertension prevalence than cART-naive. The cART, however, is not a risk factor for hypertension.

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Section: Resultssupporting

confidence: 83%

Hypertension and Related Risk Factors Among Clients on Combined Antiretroviral Therapy in Nigeria

Bello

Ojieabu

2018

Bangla Pharma J

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“…The hypertension occurrence was considerably greater in patients on cART as compared to cART-naïve patients. This observation corroborates with previous studies of Lichtenstein et al [15], Pefura Yone et al [16], Ekali et al [17], Muhammad et al [11] and Njelekela et al [18], which revealed a higher incidence of hypertension in patients on cART. Contrarily, the findings of other studies of Agrawal et al [19] indicated no disparity in the prevalence of hypertension between patients on cART and cARTnaïve patients.…”

Section: Discussionsupporting

confidence: 83%

Hypertension and Related Risk Factors among Clients on Combined Antiretroviral Therapy in Nigeria

Bello¹,

Ojieabu²

2017

J Appl Pharm

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The hypertension incidence is a major challenge in human immunodeficiency virus (HIV) infected people globally. A prospective, cross-sectional study comprising two hundred and eighteen HIV-infected patients was conducted in Antiretroviral Therapy Clinic of General Hospital, Offa between November 2015 and December 2016. Patients' blood pressure was evaluated using Omron automated blood pressure monitor following standard procedures. Dual weight and height balance was utilized to measure the weights and heights of the subjects. Hypertension incidence among patients receiving combined antiretroviral therapy (cART) was 34%, while those that were yet to start cART was 9.6%. In HIV-infected women on cART, the occurrence of hypertension was high (75.5%) as compared with men (24.5%). The hypertension pervasiveness in HIV-infected patients on cART was 75.5% in women and 24.5% in men. Risk factors that were markedly linked with hypertension among patients on cART include body mass index (OR: 3.29, 95% CI: 1.21-2.27; p<0.050), sedentary lifestyle (OR: 1.63, 95% CI: 1.20-5.38; p<0.043), age (OR: 2.17, 95% CI: 1.22-2.33; p<0.004) and gender (OR: 1.63, 95% CI: 0.85-2.41; p<0.037). Patients on cART were found to have higher hypertension prevalence than cART-naive. The cART, however, is not a risk factor for hypertension.

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“…There were 37,110 HIV-infected patients in total, with females representing approximately 28%. Thirty-one studies (61%) were conducted in low-and middleincome countries with the highest number of studies (n = 8) reported in India [22,27,29,30,45,47,59,61], followed by six studies in Nigeria [24,31,34,36,50,54], and four studies each in Brazil [23,32,41,44], Norway [15,16,55,62], and USA [17,39,40,53]. Nonetheless, studies conducted in high-income countries were generally larger in size (n = 30,120 participants), compared with studies conducted in low-and middleincome countries (n = 7488).…”

Section: Resultsmentioning

confidence: 98%

Impact of antiretroviral therapy on serum lipoprotein levels and dyslipidemias: A systematic review and meta-analysis

Nduka

Sarki

Uthman

et al. 2015

International Journal of Cardiology

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Fasting blood glucose and insulin sensitivity are unaffected by HAART duration in Cameroonians receiving first-line antiretroviral treatment

Cited by 28 publications

References 28 publications

Hypertension and Related Risk Factors Among Clients on Combined Antiretroviral Therapy in Nigeria

Hypertension and Related Risk Factors Among Clients on Combined Antiretroviral Therapy in Nigeria

Hypertension and Related Risk Factors among Clients on Combined Antiretroviral Therapy in Nigeria

Impact of antiretroviral therapy on serum lipoprotein levels and dyslipidemias: A systematic review and meta-analysis

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