Fat Embolism Syndrome

Piolanti, Marco; Dalpiaz, Giorgia; Scaglione, Mariano; Coniglio, Carlo; Miceli, Marco; Violini, Sara; Trisolini, Rocco; Barozzi, Libero

doi:10.1097/rct.0000000000000376

Cited by 19 publications

(8 citation statements)

References 36 publications

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“…Chest radiography is normal in majority of patients. CT thorax may show bilateral ground glass opacities which are well demarcated 11, 17. CT scan chest of our patient has already been described above.…”

Section: Discussionsupporting

confidence: 72%

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Clinical characteristics and management of patients with fat embolism syndrome in level I Apex Trauma Centre

Aggarwal

Banerjee

Soni

et al. 2019

Chinese Journal of Traumatology

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Purpose Fat embolism syndrome (FES) is systemic manifestation of fat emboli in the circulation seen mostly after long bone fractures. FES is considered a lethal complication of trauma. There are various case reports and series describing FES. Here we describe the clinical characteristics, management in ICU and outcome of these patients in level I trauma center in a span of 6 months. Methods In this prospective study, analysis of all the patients with FES admitted in our polytrauma intensive care unit (ICU) of level I trauma center over a period of 6 months (from August 2017 to January 2018) was done. Demographic data, clinical features, management in ICU and outcome were analyzed. Results We admitted 10 cases of FES. The mean age of patients was 31.2 years. The mean duration from time of injury to onset of symptoms was 56 h. All patients presented with hypoxemia and petechiae but central nervous system symptoms were present in 70% of patients. The mean duration of mechanical ventilation was 11.7 days and the mean length of ICU stay was 14.7 days. There was excellent recovery among patients with no neurological deficit. Conclusion FES is considered a lethal complication of trauma but timely management can result in favorable outcome. FES can occur even after fixation of the fracture. Hypoxia is the most common and earliest feature of FES followed by CNS manifestations. Any patient presenting with such symptoms should raise the suspicion of FES and mandate early ICU referral.

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Section: Discussionsupporting

confidence: 72%

“…CT thorax may show bilateral ground glass opacities which are well demarcated. 11 , 17 CT scan chest of our patient has already been described above. Treatment is mainly supportive.…”

Section: Discussionmentioning

confidence: 59%

Clinical characteristics and management of patients with fat embolism syndrome in level I Apex Trauma Centre

Aggarwal

Banerjee

Soni

et al. 2019

Chinese Journal of Traumatology

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“…The amount of lung showing GGO correlates with disease severity (30). Airspace consolidation is distributed in a gravity-dependent distribution similar to ARDS (31). It is important to note that early cases of FES might have a virtually negative assessment on CT (31).…”

Section: Pulmonary Edema Resulting From Various Conditions/diseasesmentioning

confidence: 99%

“…Airspace consolidation is distributed in a gravity-dependent distribution similar to ARDS (31). It is important to note that early cases of FES might have a virtually negative assessment on CT (31). Relevant imaging findings peak approximately 48 h after the post-traumatic release of fat.…”

Section: Pulmonary Edema Resulting From Various Conditions/diseasesmentioning

confidence: 99%

Imaging findings of pulmonary edema: Part 2. Infrequent or unusual pulmonary edema with definitive imaging findings

et al. 2019

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Pulmonary edema is a common condition with numerous causes, some of which are infrequently encountered. This review article describes various uncommon conditions/disease that are associated with pulmonary edema and which show characteristic imaging findings on chest computed tomography or other imaging modality. Thus, this review reflects the variety of factors involved in this frequently encountered condition. We demonstrate the wide range of situations that lead to the development of pulmonary edema by showing the imaging findings of unique cases. These rare varieties of pulmonary edema have distinctive imaging and clinical features that aid in providing an accurate diagnosis.

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“…Piolanti et al. demonstrated that plain CT findings are not specific for diagnosing FES 6 . Furthermore, since FES is formed from small fat particles mainly distributed in the periphery, 7 abnormal findings on CTPA are very rare 8 .…”

Section: Discussionmentioning

confidence: 99%