Fat Transplantation Using Fresh Versus Frozen Fat

Collagenase-Assisted Fat Dissociation for Autologous Fat Transfer

“…These trials have shown improved viability of digested fat to approximately 83.7%. It is difficult to compare this objective assessment of viability to previous results in the literature that involved inconsistent measurements of viability, histopathology on formalin‐fixed tissue, or subjective physician assessments 4,8 . However, from careful review of the literature, graft longevity as a clinical metric of viability has noted greater than 50% loss on average 2,3 .…”

A Double-Blind, Comparative Study of Nonanimal-Stabilized Hyaluronic Acid versus Human Collagen for Tissue Augmentation of the Dorsal Hands

“…Aging of the hands is an often‐neglected area by cosmetic surgeons. Resurgence in the examination of the aging hand, both in delineating the aesthetics of the hand and in volumetric options for intrinsic aging, is occurring 2,4 . Previous therapies targeted mostly the extrinsic signs of aging of hands such as actinic keratosis, solar lentigines, punctate hypopigmentation, and solar purpura.…”

“…Intrinsic problems with volume have largely been neglected, with only autologous fat transplantation utilized to replace volume in the hand 8 . Indeed, multiple studies on autologous fat transplantation examined technique, centrifuged versus noncentrifuged fat, and fresh versus frozen fat 3,4,8,9 . Few studies have looked beyond this filler for volumetric correction.…”

“…Current methods of hand rejuvenation include autologous fat injection, sclerotherapy, intense pulsed light, chemical peel, and microdermabrasion 3,4 . Of these, only autologous fat injection restores dermal thinning but is relatively invasive.…”