Fatal accidental ingestion of 35 % hydrogen peroxide by a 2-year-old female: case report and literature review

Background: children are exposed to numerous chemicals, such as hand sanitizers and their associated poisoning. Awareness of such poisoning symptoms and their management is critical for healthcare providers, as it can induce dangerous conditions. This study evaluated the clinical and paraclinical parameters of children who ingested hand sanitizers. Methods: In the first 6 months of 2020, the cases of children who accidentally ingested hand sanitizer and were referred to Akbar Hospital in Mashhad City, Iran (Referral pediatric poisoning center) were evaluated in this cross-sectional study. The relevant medical information and laboratory parameters were recorded. Results: In total, 20 patients were evaluated; of whom, 80% were male. The Mean±SD age of the study subjects was 4.9±4.2 years (2-15y). The ingestion was accidental in the study participants. The amount of ingestion approximately equaled a sip (3-7cc). All clinical and laboratory parameters were normal according to their age. Only 1(5%) case presented metabolic acidosis. No study subject manifested hypoglycemia or the loss of consciousness. Thus, they only received supportive care and were observed for ≥12 hours. Conclusion: Based on the present study results and absence of symptoms in the explored cases of hand sanitizer ingestion, the suitability of hand sanitizer solutions. Therefore, the formulation of these products should be carefully evaluated

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“…This is a strong oxidizing liquid. It might cause symptoms similar to consuming a caustic substance [10].…”

Section: Discussionmentioning

confidence: 99%

The Outcomes of Accidental Ingestion of Hand Sanitizer

Alizadeh

Moazen

Pourbadakhshan

et al. 2021

IJMTFM

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“…Hydrogen peroxide is a common over-the-counter solution that has developed a growing body of literature regarding toxic ingestion[ 1 - 5 ]. The main mechanisms for toxicity include direct lipid peroxidation, oxygen gas production, and corrosive injury[ 1 ].…”

Section: Introductionmentioning

confidence: 99%

Hydrogen peroxide ingestion with injury to upper gastrointestinal tract

Martin¹,

Sugawa²

2017

WJCC

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Hydrogen peroxide is a common over-the-counter solution that has developed a growing body of literature regarding toxic ingestion. Intentional ingestion of high concentration hydrogen peroxide for health purposes has gained popularity in certain patient populations; purported benefits are due to the increased oxygen released into the blood stream. We present for evaluation one such case with associated imaging that presented to our urban medical center. A brief review of the literature was also performed noting current recommendations regarding both outcomes and indications for endoscopy as well as hyperbaric oxygen therapy following ingestion of hydrogen peroxide. Our patient was a 51-year-old white female who presented with foamy hematemesis after ingesting 10 drops of 35% hydrogen peroxide as part of a home remedy to cleanse her colon and improve blood oxygenation. In addition to hematemesis, she also reported diffuse abdominal pain with sore throat and hoarse voice. Her imaging demonstrated portal venous gas and gastric edema. She was admitted for hyperbaric oxygen therapy and underwent upper endoscopy demonstrating diffuse esophagitis and gastritis with white exudate and multiple petechiae. She was later discharged home in stable condition and was lost to follow-up.

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Toxin- and Drug-Induced Pathologies

Dettmeyer¹

2018

Forensic Histopathology

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Fatal accidental ingestion of 35 % hydrogen peroxide by a 2-year-old female: case report and literature review

Cited by 8 publications

References 22 publications

The Outcomes of Accidental Ingestion of Hand Sanitizer

The Outcomes of Accidental Ingestion of Hand Sanitizer

Hydrogen peroxide ingestion with injury to upper gastrointestinal tract

Toxin- and Drug-Induced Pathologies

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