“…A slow, continuous infusion of gas (0.3 ml/kg/min) into venous circulation may be absorbed across the pulmonary capillary bed without significant clinical impact. At higher infusion rates, bubbles in pulmonary arterioles can trigger cytokine release and neutrophil activation, with subsequent pulmonary vasocon- [16] 1988 4 mo F Endoscopy of Kasai limb VGE, death Kasai procedure 3 [21] 1988 23 yr F ERCP, sphincterotomy Portal venous gas Sphincterotomy 4 [8] 1990 10 yr F Endoscopy of Kasai limb VGE, death Kasai procedure, varices 5 [5] 1994 66 yr F EGD Cerebral gas embolus, death Duodenocaval fistula 6 [2] 1994 31 yr M ERCP, sphincterotomy Portal venous gas Sphincterotomy 7 [14] 1995 56 yr M Gastroscopy VGE, death Gastric ulcer 8 [15] 1997 63 yr F ERCP, sphincterotomy VGE, death Sphincterotomy ERCP, endoscopic retrograde cholangiopancreatography; EGD, esophagogastroduodenoscopy; VGE, venous gas embolism. striction, bronchospasm, and pulmonary edema.…”