Fatal bilateral pneumothoraces following administration of aerosolised pentamidine

Green, Alison; Milne, Nathan; Ong, Boon Hoong

doi:10.1016/j.jflm.2011.06.012

Cited by 4 publications

(1 citation statement)

References 38 publications

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“…Currently, the material data safety sheet states “Inhalation of dusts, generated by the material, during the course of normal handling, may produce toxic effects.” Although these toxic effects are not defined and do not include pneumothorax. Other irritant gasses 2–5 inhaled illicit substances 6–10 and inhaled medications 11 have all been previously implicated as causes of pneumothorax in the literature. For example, at high concentrations, partially water‐soluble chlorine gas has shown to cause respiratory distress when inhaled, because of the development of bronchospasm and pulmonary edema 12 .…”

Section: Discussionmentioning

confidence: 99%

Pneumothorax associated with accidental 4‐nitrophenyl chlonoformate inhalation in an academic chemistry lab

Imler

Martel

2023

JACEP Open

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Section: Discussionmentioning

confidence: 99%

Pneumothorax associated with accidental 4‐nitrophenyl chlonoformate inhalation in an academic chemistry lab

Imler

Martel

2023

JACEP Open

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Bilateral spontaneous pneumothorax secondary to aspiration pneumonia induced by a wristwatch lodged at the pharyngoesophageal junction

Kawai

Miyao

Kotani

et al. 2015

Forensic Sci Med Pathol

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Bilateral spontaneous pneumothorax secondary to disease is rare and seldom encountered in forensic autopsies; however, traumatic bilateral pneumothorax occurs often. Herein, we present a forensic case involving a 50-year-old woman who died 4 days after ingesting a wristwatch. Postmortem computed tomography and autopsy findings demonstrated that the wristwatch was lodged at the pharyngoesophageal junction, that she had a bilateral pneumothorax unaccompanied by any thoracic wound, and that macular hemorrhagic lesions on the lung surfaces were responsible for the pneumothorax. A histological examination of the macular lesions revealed that they were aspiration pneumonia foci with many birefringent foreign materials. Furthermore, a necrotic process secondary to aspiration pneumonia with a one way check-valve hyperinflation caused by foreign materials in the bronchioles was the most probable pathogenesis of her pneumothorax. To our knowledge, this is the first reported case of a bilateral secondary spontaneous pneumothorax caused by a large foreign body at the pharyngoesophageal junction leading to death.

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Pleurotoxic Drugs—an Update: Someone Else to Blame?

Skouras

Kalomenidis

2019

Curr Pulmonol Rep

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Fatal bilateral pneumothoraces following administration of aerosolised pentamidine

Cited by 4 publications

References 38 publications

Pneumothorax associated with accidental 4‐nitrophenyl chlonoformate inhalation in an academic chemistry lab

Pneumothorax associated with accidental 4‐nitrophenyl chlonoformate inhalation in an academic chemistry lab

Bilateral spontaneous pneumothorax secondary to aspiration pneumonia induced by a wristwatch lodged at the pharyngoesophageal junction

Pleurotoxic Drugs—an Update: Someone Else to Blame?

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