Fatal colonic explosion during colonoscopic polypectomy

Bigard, M A; Gaucher, P; Lassalle, Claude

doi:10.1016/0016-5085(79)90172-0

Cited by 169 publications

(37 citation statements)

References 9 publications

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“…2 Mannitol was used in early formulations but abandoned secondary to bacterial fermentation into hydrogen and methane gas, which can cause explosion when electrocautery is used. 1,44 Evidence. Although these regimens are effective in cleansing the colon, they are poorly tolerated.…”

Section: High-volume Gut Lavagementioning

confidence: 99%

A Consensus Document on Bowel Preparation Before Colonoscopy: Prepared by a Task Force From The American Society of Colon and Rectal Surgeons (ASCRS), The American Society for Gastrointestinal Endoscopy (ASGE), and The Society of American Gastrointestinal and Endoscopic Surgeons (SAGES)

Wexner

Beck

Baron

et al. 2006

Diseases of the Colon &Amp; Rectum

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Section: High-volume Gut Lavagementioning

confidence: 99%

A Consensus Document on Bowel Preparation Before Colonoscopy: Prepared by a Task Force From The American Society of Colon and Rectal Surgeons (ASCRS), The American Society for Gastrointestinal Endoscopy (ASGE), and The Society of American Gastrointestinal and Endoscopic Surgeons (SAGES)

Wexner

Beck

Baron

et al. 2006

Diseases of the Colon &Amp; Rectum

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“…Other side events like vomiting and nausea may be less troublesome if the palatability is improved with taste substances or if the emptying process of the stomach is accelerated with parenteral erythromycin. Sorbitol may replace mannitol to avoid the degradation to methane with the risk of explosion [21]. Potential side effects from electrolytic disturbances may be avoided if extra water is ingested, but further studies are required to evaluate the extent of electrolytic imbalance from osmosis.…”

Section: Discussionmentioning

confidence: 97%

Osmolarity: a decisive parameter of bowel agents in intestinal magnetic resonance imaging

et al. 2006

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The aim was to evaluate the importance of the osmolarity of different oral agents for bowel distension and the level of related adverse events. The longitudinal design included the exposition of different oral MR agents on two separate occasions. Four groups of volunteers were randomly given 350 ml gastrografin of three different concentrations and water. On the second occasion they received mannitol, iohexol or iodixanol with equivalent osmolarities, but the control group (water) received mannitol. We recorded the outcomes as the degree of bowel distension determined as the mean bowel section area and the total level of discomfort recorded from a visual analogue scale (VAS). The statistical analysis included scatter plots with the best-fitted line with linear regression to study the association between osmolarity and section area and the association between osmolarity and adverse events. A dose-response association was found between increasing osmolarity levels and bowel area in square centimeters (P = 0.00001). A similar dose-response association existed between increasing levels of osmolarity and adverse events (P = 0.001). Osmolarity appears to be more important for bowel distension than the physico-chemical characteristics of the nonabsorbable oral agents. The optimum osmolarity level is determined by the patient's tolerance of the adverse events.

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“…Insufflation of carbon dioxide during colonoscopy significantly reduces abdominal pain after examination [1,7,[9][10][11][12][13][14][15][16][17][18][19] because of a more rapid resorption of carbon dioxide from the colon [8,20] and excretion through the lung [7]. The use of carbon dioxide during colonoscopic examination was first suggested in 1950 because of safety during electrosurgical polypectomies [21][22][23][24] but reducing discomfort was observed [25,26].…”

Section: Discussionmentioning

confidence: 99%