Fatal Systemic Nocardia Infection Revealed by Cardiac Tamponade

Roubille, François; Maxant, Guillaume; Serre, Isabelle; Colson, P; Battistella, Pascal; Calvet, Brigitte; Albat, Bernard; Pasquié, Jean‐Luc

doi:10.2169/internalmedicine.49.2478

Cited by 5 publications

(2 citation statements)

References 6 publications

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“…For example, Nocardia spp . has been reported to cause purulent pericarditis [2, 3], cardiac tamponade [4], anterior mediastinal mass [5, 6], and mimicking pancoast tumor [7]. These reports of fatal involvement of the pericardium emphasize the necessity of early surgical intervention.…”

Section: Discussionmentioning

confidence: 99%

First Report ofNocardia asiaticaPresenting as an Anterior Mediastinal Mass in a Patient with Myasthenia Gravis: A Case Report and Review of the Literature

El-Herte

Kanj²,

Araj³

et al. 2012

Case Reports in Infectious Diseases

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The spectrum of infections with Nocardia spp. is heterogeneous. It has classically been associated with lung, brain, or skin involvement. We describe an unusual presentation of Nocardia asiatica (N. asiatica) in an Iraqi patient with myasthenia gravis suffering from a disseminated infection and presenting with an anterior mediastinal cystic mass. N. asiatica has only been three times described outside Japan and Thailand, and the rarity of this entity deserves this communication.

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Section: Discussionmentioning

confidence: 99%

First Report ofNocardia asiaticaPresenting as an Anterior Mediastinal Mass in a Patient with Myasthenia Gravis: A Case Report and Review of the Literature

El-Herte

Kanj²,

Araj³

et al. 2012

Case Reports in Infectious Diseases

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“…Cardiac involvement due to Nocardia spp. is unusual, but cases of purulent pericarditis, 195,196 cardiac tamponade, 197 and endocarditis [198][199][200][201][202] have been described.…”

Section: Cardiacmentioning

confidence: 99%

Nocardia spp.: A Rare Cause of Pneumonia Globally

Lynch

Reid

Clark

2020

Semin Respir Crit Care Med

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AbstractMembers of the Nocardia genus are ubiquitous in the environment. These aerobic, gram-positive organisms can lead to life-threatening infection, typically in immunocompromised hosts such as solid organ transplant recipients or those receiving immunosuppressive medications for other reasons. This current review discusses the microbiology of nocardiosis, risk factors for infection, clinical manifestations, methods for diagnosis, and treatment. Nocardiosis primarily affects the lung but may also cause skin and soft tissue infection, cerebral abscess, bloodstream infection, or infection involving other organs. Although rare as a cause of community-acquired pneumonia, Nocardia can have severe morbidity and mortality, particularly in patients with comorbidities or compromised immunity. Early diagnosis and timely initiation of therapy are critical to optimizing patient outcomes. Species identification is important in determining treatment, as is in vitro susceptibility testing. Sulfonamide therapy is usually indicated, although a variety of other antimicrobials may be useful, depending on the species and susceptibility testing. Prolonged therapy is usually indicated, for 6 to 12 months, and in some cases surgical debridement may be required to resolve infection.

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