Fatal traumatic brain injuries during 13 years of successive alcohol tax increases in Finland – a nationwide population-based registry study

Posti, Jussi P.; Sankinen, Matti; Sipilä, Jussi; Ruuskanen, Jori O.; Rinne, Jaakko; Rautava, Päivi; Kytö, Ville

doi:10.1038/s41598-019-41913-8

Cited by 14 publications

(13 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Both studies used a civil registration and vital statistics system that was representative of the entire country. However, the TBI-related mortality among males was higher in Seychelles than reported in studies from Austria and Ecuador, but lower than in Finland and in the USA (24,(32)(33)(34)(35). The fairly high rates in Seychelles may be partly attributed to the high road traffic injury mortality rates, consistent with high rates in LMICs but was also lower (17.5%) than the global average of 23% (28,36).…”

Section: Discussionmentioning

confidence: 59%

Changes in Mortality Related to Traumatic Brain Injuries in the Seychelles from 1989 to 2018

et al. 2021

Self Cite

View full text Add to dashboard Cite

Introduction: Traumatic Brain Injuries (TBIs) are a significant source of disability and mortality, which disproportionately affect low- and middle-income countries. The Republic of Seychelles is a country in the African region that has experienced rapid socio-economic development and one in which all deaths and the age distribution of the population have been enumerated for the past few decades. The aim of this study was to investigate TBI-related mortality changes in the Republic of Seychelles during 1989–2018.Methods: All TBI-related deaths were ascertained using the national Civil Registration and Vital Statistics System. Age- and sex-standardised mortality rates (per 100,000 person-years) were standardised to the age distribution of the World Health Organisation standard population.Results: The 30-year age-standardised TBI-related mortality rates were 22.6 (95% CI 19.9, 25.2) in males and 4.0 (95% CI 2.9, 5.1) in females. Road traffic collisions were the leading contributor to TBI-related mortality [10.0 (95% CI 8.2, 11.8) in males and 2.7 (95% CI 1.8, 3.6) in females, P > 0.05]. TBI-related mortality was most frequent at age 20–39 years in males (8.0) and at age 0–19 in females (1.4). Comparing 2004–2018 vs. 1989–2003, the age-standardised mortality rates changed in males/females by −20%/−11% (all cause mortality), −24%/+39.4% (TBIs) and +1%/+34.8% (road traffic injury-related TBI).Conclusion: TBI-related mortality rates were much higher in males but decreased over time. Road traffic collisions were the single greatest contributor to TBI mortality, emphasising the importance of road safety measures.

show abstract

Section: Discussionmentioning

confidence: 59%

Changes in Mortality Related to Traumatic Brain Injuries in the Seychelles from 1989 to 2018

et al. 2021

Self Cite

View full text Add to dashboard Cite

show abstract

“…Direct causal associations with the current results cannot be drawn, but the earlier findings help contextualize the findings of our study. Since both alcohol consumption and abuse are much more common among men in Finland [25], this might also explain the sex differences we observed.…”

Section: Discussionmentioning

confidence: 95%

High-Risk Periods for Adult Traumatic Brain Injuries: A Nationwide Population-Based Study

et al. 2021

Self Cite

View full text Add to dashboard Cite

Introduction: There is minimal existing available information on nationwide seasonal peaks in traumatic brain injuries (TBIs). This lack of information is an impediment to the effective development of prevention programs, societal policies, and hinders the resourcing of medical emergency services. Our current aim is to study nationwide population-based high-risk periods TBI over a 15-year study period in Finland. Methods: Nationwide databases were searched for all admissions with a TBI diagnosis and later for deaths of persons ≥16 years of age during 2004–2018. The search included all hospitals that provide acute TBI care in Finland. Results: The study period included 69,231 TBI-related hospital admissions (men = 62%). We found that for men, the highest rate of TBIs occurred on Saturdays, whereas women experience the highest rate of TBIs on Mondays. The highest rate of TBIs in men occurred in July, while women experienced the highest rate of TBIs in January. TBI-related hospital admissions (incidence risk ratio [IRR] 1.090, 95% CI 1.07–1.11, p < 0.0001) and mortality within 30 days after TBI (hazard ratio [HR] 1.057, 95% CI 1.001–1.116, p = 0.0455) were more common on public holidays and weekends than on weekdays. There was an increasing trend in the proportion of TBI-related hospital admissions occurring on public holidays and weekends from 2004 (31.5%) to 2018 (33.4%) (p = 0.0007). In summer months, TBI-related hospital admissions (IRR 1.10, 95% CI 1.08–1.12, p < 0.0001) and 30-day mortality (HR 1.069, 95% CI 1.010–1.131, p = 0.0211) were more common than in other months. TBIs occurred more often in younger and healthier individuals on these index days and times. In terms of specific public holidays, the TBI risk was overall higher on New Year’s Eves and Days (IRR 1.40, 95% CI 1.25–1.58, p < 0.0001) and Midsummer’s Eves and Days (IRR 1.36, 95% CI 1.20–1.54, p < 0.0001), compared to nonworking days. This finding was significant in both genders. Conclusions: TBI-related hospital admissions and mortality were more common on public holidays, weekends, and in summer months in Finland. People who sustained TBIs on these days were on average younger and healthier. The occurrence of TBIs on public holidays and weekends is increasing at an alarming rate.

show abstract

“…Infective endocarditis was recognized by International Classification of Diseases, Tenth Revision (ICD-10) codes I33, I38 or I39. Age- and sex-specific population and mortality data of the Finnish population from the years 2004–2016 were obtained from Statistics Finland [14]. The study period included 28,657,870 person-years and 651,556 total deaths.…”

Section: Methodsmentioning

confidence: 99%

“…The associations of age, sex and study year with the incidence rate and proportion of deaths were studied by using Poisson regression modeling. Incidence rate and proportionate amount of deaths were modelled with using the logarithm of corresponding population or number of deaths as an offset parameter [14]. Impact of age on associations with sex were studied with interaction analysis.…”

Section: Methodsmentioning

confidence: 99%

Occurrence of fatal infective endocarditis: a population-based study in Finland

et al. 2019

Self Cite

View full text Add to dashboard Cite

BackgroundInfective endocarditis (IE) is a serious mainly bacterial infection associated with high mortality. Epidemiology of fatal IE is however largely unknown. We studied occurrence and trends of fatal IE in a population-based setting.MethodsAll adults (≥18 years of age) who deceased due to IE in Finland during 2004–2016 were studied. Data was collected from the nationwide, obligatory Cause of Death Registry. Background population consisted of 28,657,870 person-years and 651,556 deaths.ResultsInfective endocarditis contributed to death in 754 cases and was the underlying cause of death in 352 cases. The standardized incidence rate of deaths associated with IE was 1.42 (95% confidence interval (CI): 1.32–1.52) per 100,000 person-years. Incidence rate increased progressively with aging from 50 years of age. Men had a two-fold risk of acquiring fatal infective endocarditis compared to women (risk ratio (RR) 1.95; 95% CI: 1.71–2.22; P < 0.0001). On average, IE contributed to 1.16 (95% CI: 1.08–1.24) out of 1000 deaths in general adult population. The proportionate amount of deaths with IE was highest in population aged < 40 years followed by gradual decrease with aging. Incidence rate and proportion of deaths caused by IE remained stable during the study period.ConclusionsOur study describes for the first time the population-based epidemiology of fatal IE in adults. Men had a two-fold risk of acquiring fatal IE compared to women. Although occurrence of fatal IE increased with aging, the proportion of deaths to which IE contributed was highest in young adult population.

show abstract

Fatal traumatic brain injuries during 13 years of successive alcohol tax increases in Finland – a nationwide population-based registry study

Cited by 14 publications

References 17 publications

Changes in Mortality Related to Traumatic Brain Injuries in the Seychelles from 1989 to 2018

Changes in Mortality Related to Traumatic Brain Injuries in the Seychelles from 1989 to 2018

High-Risk Periods for Adult Traumatic Brain Injuries: A Nationwide Population-Based Study

Occurrence of fatal infective endocarditis: a population-based study in Finland

Contact Info

Product

Resources

About