Fate of coronary aneurysms in Kawasaki disease: Serial coronary angiography and long-term follow-up study

Kato, Hirohisa; Ichinose, Eisei; Yoshioka, Fumio; Takechi, T; Matsunaga, Shingi; Suzuki, Kazushige; Rikitake, Noriko

doi:10.1016/0002-9149(82)90256-9

Cited by 431 publications

(147 citation statements)

References 10 publications

Supporting

Mentioning

143

Contrasting

Order By: Relevance

“…24) Administration of IVIG reduced the prevalence of CAA in Japan from 15-25% in children treated with aspirin alone 25,26) to 4-12% in those who were treated with IVIG and aspirin. [27][28][29] We have been using the same combination of IVIG and aspirin with good results.…”

Section: Discussionmentioning

confidence: 99%

<b>Kawasaki Disease</b>

et al. 2005

View full text Add to dashboard Cite

SUMMARYKawasaki disease (KD) has not been frequently reported from developing countries, especially from India. In this series from a tertiary level center in North India, we report on the clinical features and management of patients with KD seen between January 1994 to November 2004. KD was diagnosed on the basis of standard diagnostic criteria. Investigations included work-up for other causes of fever along with chest X-rays, electrocardiograms, and 2-D echocardiography. Thallium scintigraphy and coronary angiography were performed in 20 and 3 cases, respectively. Sixty-nine children (49 boys and 20 girls) fulfilled the diagnostic criteria. Mean age at diagnosis was 4.9 ± 3.0 years (range 0.3-14 years) and as many as 23 cases (33.3%) were above 5 years of age. Clustering was seen during the winter months. Extreme irritability, out of proportion to the degree of fever, was a characteristic feature. Redness of the lips and tongue was common but rash was seen only in 43 cases and lymphadenopathy in 47 cases. Thrombocytosis was present in 52.2% of the patients. Sixty-four patients received intravenous immunoglobulin. Cardiac abnormalities included extrasystoles in 1, coronary artery dilatation in 5, valvular regurgitation in 3, and perfusion defects on thallium scintigraphy in 4. There was no mortality. KD appears to occur at an older age in Indian children as compared to reports from Japan. Irritability is a characteristic clinical finding. Cardiac abnormalities are frequent during the acute stage but regress gradually. The disease needs to be considered in the differential diagnosis of all children with persistent unexplained fever. (Int Heart J 2005; 46: 679-689)

show abstract

Section: Discussionmentioning

confidence: 99%

<b>Kawasaki Disease</b>

et al. 2005

View full text Add to dashboard Cite

show abstract

“…As aneurysmal regression takes place primarily during the first 6 months to 2 years after the acute illness (Kato et al 1975(Kato et al , 1982, the patient should be followed for at least 2 years. In our patient, the 5 year follow-up CAG revealed an aggravation of the coronary lesions, which could have produced a myocardial infarction; thus surgical intervention was indicated.…”

Section: Discussionmentioning

confidence: 99%

“…Coronary aneurysms occur in 15 % of the patients with Kawasaki disease (Kawasaki, 1969), of which half regressed to normal (Kato et al 1982). This and subsequent coronary involvement, thrombotic occlusion and coronary stenosis, may lead to myocardial damage including myocardial infarction, which is suspected as the most common cause of sudden death (Fujiwara and Hamashima, 1978).…”

Section: Introductionmentioning

confidence: 99%

A case report of coronary revascularization for Kawasaki disease.

et al. 1986

Self Cite

View full text Add to dashboard Cite

“…Angiographic and echocardiographic studies have documented coronary artery aneurysms in 25% of untreated patients [2,3]. Studies of the natural history of these lesions suggest that they may either remodel as a result of myointimal proliferation, or may persist and develop stenosis of the vessel lumen at the outlet of the aneurysm [3].…”

Section: Introductionmentioning

confidence: 99%