Fatigue and associated factors in maintenance hemodialysis patients

Nakahara, Noriko; Nishiguchi, Kazumi; Izumi, N.; Tsurusaki, Kiyoshi; Kusumoto, Hiromi; Arakawa, Masahiro; Fujiwara, Kazutoshi

doi:10.4009/jsdt.52.477

Cited by 1 publication

(1 citation statement)

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“…Fatigue is strongly associated with prognosis, and that is a powerful independent predictor of cardiovascular disturbance [35]. Compared with healthy people, hemodialysis patients feel fatigue, and older hemodialysis patients feel more fatigue [36]. Fatigue is reported to affect on preparation of meals in HD patients and to become barrier toward dietary intake [37].…”

Section: Discussionmentioning

confidence: 99%

New polymethylmethacrylate membrane, NF-U, improves nutritional status and reduces patient-reported symptoms in older dialysis patients

Chida

Ishii²,

Masakane

2022

Ren Replace Ther

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Introduction We previously reported the nutritional advantage of polymethylmethacrylate (PMMA) membranes to prevent the progression of malnutrition in dialysis patients. In this study, we examined whether a new PMMA dialyzer, NF-U, has advantages to improve the nutritional condition, patient-reported symptoms, and other clinical parameters in older dialysis patients. Methods We selected ten older chronic dialysis patients who were treated with NF-U for improving their worsening nutritional parameters and retrospectively evaluated nutrition and patient-reported symptoms. Patient-reported symptoms were surveyed by our original questionnaire including 20 items of symptom. Results Serum albumin concentration, geriatric nutritional risk index, and percent creatinine generation rate increased from 3.01 ± 0.16 to 3.25 ± 0.17 g/dL, 87.7 ± 5.8 to 91.4 ± 6.2, 100.2 ± 21.6 to 111.9 ± 20.9% at 1 and 4 months after switching to NF-U, respectively. For patient-reported outcomes, fatigue and the total score of patient-reported outcomes were improved after switching to NF-U. Conclusion Our results suggest that NF-U is a good choice for older dialysis patients to ameliorate their nutritional status and patient-reported outcomes.

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Section: Discussionmentioning

confidence: 99%