2007
DOI: 10.1097/01.ncc.0000290815.99323.75
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Fatigue and Physical Activity in Older Adults With Cancer

Abstract: Cancer is a disease predominantly affecting older adults. Cancer fatigue is the most common and often most distressing symptom associated with cancer and its treatment, often persisting months to years after treatment. Untreated cancer fatigue may lead to significant reductions in physical activity, physical functioning, and quality of life and may interfere with patients' adherence to cancer treatment. Physical activity has the strongest supporting evidence as an intervention to reduce cancer fatigue, maintai… Show more

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Cited by 71 publications
(43 citation statements)
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“…These reviews have focused on specific outcomes, primarily fatigue and quality of life, and populations, including elderly survivors, patients during treatment, or certain cancer types [4][5][6][7][8][9][10][11][12]. Galvão et al [13] provided a qualitative review of exercise intervention studies during and post treatment for all cancers, and a quantitative metaanalyses on physical activity interventions in all adult cancers was published in 2006 [14].…”
Section: Introductionmentioning
confidence: 99%
“…These reviews have focused on specific outcomes, primarily fatigue and quality of life, and populations, including elderly survivors, patients during treatment, or certain cancer types [4][5][6][7][8][9][10][11][12]. Galvão et al [13] provided a qualitative review of exercise intervention studies during and post treatment for all cancers, and a quantitative metaanalyses on physical activity interventions in all adult cancers was published in 2006 [14].…”
Section: Introductionmentioning
confidence: 99%
“…A further concern is that the average age of participants in three studies [48,50,51] is below our target population of 60 or older and the age range in the largest of the six studies [49] is only 65 to 68. A specific focus on older patients is a known gap in the physical activity-cancer related fatigue literature [12].…”
Section: Discussionmentioning
confidence: 99%
“…Fatigue in cancer patients is of clinical concern because it is associated with decreased physical activity, lower functional status, and impaired quality of life [11]. In older cancer patients, specifically, additional concerns are that long-lasting fatigue undermines function (physical performance, activities of daily living) which, in turn, can disrupt treatment regimens and increase the risk for institutional care [10,[12][13][14][15]. Among older adults in general, fatigue is a self-reported indicator of aging and frailty, signaling decreased physiologic reserves for coping with stressors and increased risk for mortality [14,15].…”
Section: Introductionmentioning
confidence: 99%
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“…[20][21][22][23][24][25][26][27] a) Fatigue, dyspnea, and sleep disturbances Symptoms of fatigue, dyspnea, and sleep disturbances (including both insomnia and hypersomnolence) are significantly elevated among individuals with cancer, ESRD, HF, and PD compared to healthy older adults. [28][29][30][31] For example, fatigue is experienced by 60%-97% of ESRD patients; 32 dyspnea is reported by over three-fourths of older adults with advanced HF; 33 and 40%-90% of PD patients report sleep disturbances. These symptoms are consistently correlated with poor quality of life and may be more common in older adults than younger individuals with the same disease.…”
Section: Summary Of the Current Evidencementioning
confidence: 99%