The treatment of carbon fiber reinforced polymer (CFRP)–metal bond interface is very important for the practical application of CFRP‐reinforced metal structures in automobile, aviation, and other transportation vehicles. In this article, the effects of different interface connection conditions on the failure mode and energy absorption of hybrid tubes were studied by experimental and simulation methods. For this purpose, the two aspects metal surface treatment (sandblasting) and connection mode (socket, co‐curing, and secondary bonding) were used for adhesive joining. By observing the force–displacement curve, the energy absorption capacity of the hybrid tube under different interface connection conditions was quantified, and the performance was evaluated. The calculation results show that the interfacial connection conditions have different effects on the crashworthiness of the hybrid tube under different loading conditions. Among them, for axial crushing and transverse bending loads, the energy absorption characteristics of the hybrid tube can be effectively improved by sandblasting and cementing. Under the action of radial compression, although the roughness of the interface is increased by sandblasting, the energy absorption capacity is reduced rather than enhanced. In order to reveal the mechanism and make parameterized definitions of the interface characteristics, so as to effectively predict the finite element model is especially necessary. With the improvement of interface bond strength, its bearing limit distribution area also increases, and the corresponding deformation is also large, which eventually leads to more energy absorption under axial crushing and transverse bending loads. The increase in the interface connection strength has little effect on its crashworthiness under radial pressure.